Mean (SD) serum creatinine levels (mg/dl; to convert values to μmol/l multiply by 88.4), creatinine clearance (ml/min), and sodium excretion (mmol/24 hours) up to one year after diagnosis of hepatorenal syndrome in 41 patients of whom 31 received a transjugular intrahepatic portosystemic stent-shunt (TIPS) and 10 were excluded from receiving TIPS. p values were calculated using the Mann-Whitney U test and represent comparisons with baseline for patients at risk or between treatment groups at given time intervals: *p<0.05, **p<0.01, ***p<0.001. Mean (SD) serum creatinine levels (mg/dl; to convert values to μmol/l multiply by 88.4), creatinine clearance (ml/min), and sodium excretion (mmol/24 hours) up to one year after diagnosis of hepatorenal syndrome in 41 patients of whom 31 received a transjugular intrahepatic portosystemic stent-shunt (TIPS) and 10 were excluded from receiving TIPS. p values were calculated using the Mann-Whitney U test and represent comparisons with baseline for patients at risk or between treatment groups at given time intervals: *p<0.05, **p<0.01, ***p<0.001. Note that all values prior to and up to one week after TIPS were determined without diuretics. Thereafter, moderate diuretic medication with furosemide (40–80 mg/day) and spironolactone (100–200 mg/day) was reintroduced and adapted to the patients’ needs. K A Brensing et al. Gut 2000;47:288-295 Copyright © BMJ Publishing Group Ltd & British Society of Gastroenterology. All rights reserved.