Frequency and kinetics of killer cell apoptosis are dependent on functional conjugations with multiple NALM-6 tumor cells. Frequency and kinetics of killer.

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Presentation transcript:

Frequency and kinetics of killer cell apoptosis are dependent on functional conjugations with multiple NALM-6 tumor cells. Frequency and kinetics of killer cell apoptosis are dependent on functional conjugations with multiple NALM-6 tumor cells. A, comparisons of the mean kinetics of effector apoptosis of individual single killer CAR+ T cells (E:T 1:1) with multikiller CAR+ T cells (E:T 1:2-5). Each circle represents a single-cell; CAR4 cells are represented by gray circles, and CAR8 cells are represented by black circles. B, frequency of killer cell apoptosis as a function of tumor cell density. *, P < 0.05; ***, P < 0.001; ****, P < 0.0001; n.s., not statistically significant. Ivan Liadi et al. Cancer Immunol Res 2015;3:473-482 ©2015 by American Association for Cancer Research