The linear decrease in TLCO as the accessible VA decreases is associated with an exponential increase in KCO. For instance, TLCO decreases ∼25% while KCO.

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Presentation transcript:

The linear decrease in TLCO as the accessible VA decreases is associated with an exponential increase in KCO. For instance, TLCO decreases ∼25% while KCO increases by ∼90% from TLC to FRC. It follows that at a given VA below TLC, KCO (% predicted) will alwa... The linear decrease in TLCO as the accessible VA decreases is associated with an exponential increase in KCO. For instance, TLCO decreases ∼25% while KCO increases by ∼90% from TLC to FRC. It follows that at a given VA below TLC, KCO (% predicted) will always be a higher value than TLCO (% predicted). See the text for further elaboration on the clinical interpretation of those measurements. VA/VA TLC%: accessible VA as a percentage of the VA found at TLC. Modified from [23] with permission from the publisher. J. Alberto Neder et al. Breathe 2019;15:69-76 ©2019 by European Respiratory Society