Challenges in assessing outcomes for pediatric asthma

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Presentation transcript:

Challenges in assessing outcomes for pediatric asthma Stanley J. Szefler, MD Journal of Allergy and Clinical Immunology Volume 107, Issue 5, Pages S456-S464 (May 2001) DOI: 10.1067/mai.2001.114947 Copyright © 2001 Mosby, Inc. Terms and Conditions

Fig. 1 Relationship between (A ) natural logarithm PC20 FEV1, (B ) prebronchodilator FEV1, and (C ) prebronchodilator FEV1/FVC (%) and asthma duration determined by multiple regression analyses adjusted for the following potential confounding parameters: age at randomization, sex, serum log IgE level, number of positive skin prick test responses, total blood eosinophil count, asthma severity, household Der p 1 level, prior use of inhaled corticosteroids and cromolyn, and clinical center. R , Spearman rank coefficient for unadjusted bivariate analysis of this relationship by simple linear regression; Pre-BD , prebronchodilator. (From Zeiger RS, Dawson C, Weiss S. Relationships between duration of asthma and asthma severity among children in the Childhood Asthma Management Program [CAMP]. J Allergy Clin Immunol 1999;103:376-87. With permission.) Journal of Allergy and Clinical Immunology 2001 107, S456-S464DOI: (10.1067/mai.2001.114947) Copyright © 2001 Mosby, Inc. Terms and Conditions