High prevalence of mutators among Enterobacter cloacae nosocomial isolates and their association with antimicrobial resistance and repetitive detection

Slides:

Advertisements

Similar presentations

Models for the organisation of hospital infection control and prevention programmes B. Gordts Clinical Microbiology and Infection Volume 11, Pages

Advertisements

C.-S. Lee, J.-H. Lee Clinical Microbiology and Infection

Distribution of phylogenetic groups, sequence type ST131, and virulence-associated traits among Escherichia coli isolates from men with pyelonephritis.

R. Dumke, H. von Baum, P.C. Lück, E. Jacobs

L. Boyanova Clinical Microbiology and Infection

High prevalence of azithromycin resistance to Treponema pallidum in geographically different areas in China X.-S. Chen, Y.-P. Yin, W.-H. Wei, H.-C. Wang,

Gut bacterial microbiota and obesity

Molecular characterization of methicillin-resistant Staphylococcus aureus isolated over a 2-year period in a Qatari hospital from multinational patients

S. Wagenpfeil, A. Neiss, K. Banz, P. Wutzler

P. Clarke, S. Murchan, E.G. Smyth, H. Humphreys

Herpes zoster in non-hospitalized children

C.-S. Lee, J.-H. Lee Clinical Microbiology and Infection

High prevalence of multidrug-resistant Pneumococcal molecular epidemiology network clones among Streptococcus pneumoniae isolates from adult patients.

Membrane permeability, a pivotal function involved in antibiotic resistance and virulence in Enterobacter aerogenes clinical isolates J.-P. Lavigne,

Gentamicin susceptibility in Escherichia coli related to the genetic background: problems with breakpoints L. Jakobsen, D. Sandvang, V.F. Jensen, A.M.

Quinolone resistance among Shigella spp

Genital Chlamydia trachomatis infections

Multicentre surveillance of prevalence of the 23S rRNA A2058G and A2059G point mutations and molecular subtypes of Treponema pallidum in Taiwan, 2009–2013

P. Nordmann, L. Poirel Clinical Microbiology and Infection

Antimicrobial drug use and infection control practices associated with the prevalence of methicillin-resistant Staphylococcus aureus in European hospitals

Membrane permeability, a pivotal function involved in antibiotic resistance and virulence in Enterobacter aerogenes clinical isolates J.-P. Lavigne,

Chlamydia trachomatis infections in heterosexuals attending sexually transmitted disease clinics in Slovenia D. Kese, M. Maticic, M. Potocnik Clinical.

Potential risk factors for infection with Candida spp

Clinical Microbiology and Infection

Surveillance of Legionnaires’ disease in Austria

A multicentre analysis of epidemiology of the nosocomial bloodstream infections in Japanese university hospitals M. Nagao Clinical Microbiology and.

Vector control: a cornerstone in the malaria elimination campaign

Sofie Arens, Jan Verhaegen, Ludo Verbist

Multicenter study of the in vitro activity of cefepime in comparison with five other broad- spectrum antibiotics against clinical isolates of Gram-positive.

Mechanisms of quinolone resistance in clinical isolates of Enterobacter cloacae Apostolos Georgopoulos, Robert Schein, Astrid Buxbaum, Susan Tzotzos,

Antibiotic resistance patterns of Escherichia coli isolates from different aquatic environmental sources in Leon, Nicaragua E. Amaya, D. Reyes, M. Paniagua,

Comparative assessment of inoculum effects on the antimicrobial activity of amoxycillin- clavulanate and piperacillin-tazobactam with extended-spectrum.

Comparative in vitro pharmacodynamics of BO-2727, meropenem and imipenem against Gram-positive and Gram-negative bacteria Inga Odenholt, Elisabeth Löwdin,

Rapid identification of uropathogenic Escherichia coli of the O25:H4-ST131 clonal lineage using the Diversi-Lab repetitive sequence-based PCR system

Microbiological and epidemiological studies of Enterococcus faecium resistant to amoxycillin in a university hospital in eastern France M. Thouverez,

Antimicrobial susceptibility in Escherichia coli of human and avian origin—a comparison of wild-type distributions M. Sjölund, S. Bengtsson, J. Bonnedahl,

Incidence, risk factors and outcomes of Escherichia coli bloodstream infections in a large Canadian region K.B. Laupland, D.B. Gregson, D.L. Church,

Close cooperation between infectious disease physicians and attending physicians can result in better management and outcome for patients with Staphylococcus.

Metagenomics and probiotics

M. Aires-de-Sousa Clinical Microbiology and Infection

T.M. File Clinical Microbiology and Infection

Long-term study of the frequency of Escherichia coli and Klebsiella pneumoniae isolates producing extended-spectrum β-lactamases L. Romero, L. López,

Update on antifungal resistance in Aspergillus and Candida

Harmonised monitoring of antimicrobial resistance in Salmonella and Campylobacter isolates from food animals in the European Union S. Bronzwaer Clinical.

Abstracts cont. Clinical Microbiology and Infection

Distribution of phylogenetic groups, sequence type ST131, and virulence-associated traits among Escherichia coli isolates from men with pyelonephritis.

Pandemic lineages of extraintestinal pathogenic Escherichia coli

Detection of nosocomial Clostridium difficile infections with toxigenic strains despite negative toxin A and B testing on stool samples J. Stahlmann,

Circulation of international clones of levofloxacin non-susceptible Streptococcus pneumoniae in Taiwan Y.-C. Hsieh, L.-Y. Chang, Y.-C. Huang, H.-C. Lin,

C. Gagliotti, L. Nobilio, M.L. Moro

Prevalence and diversity of extended-spectrum ß-lactamases in faecal Escherichia coli isolates from healthy humans in Spain L. Vinué, Y. Sáenz, S. Martínez,

An after-hours clinical liaison blood culture service—is it worth it?

G.M. Rossolini, E. Mantengoli Clinical Microbiology and Infection

Statin use and clinical outcomes among pneumonia patients

Clinical Microbiology and Infection

Distribution and clonal relationship of cell surface virulence genes among Streptococcus pneumoniae isolates in Japan S. Imai, Y. Ito, T. Ishida, T.

Antibiotic resistance patterns of more than clinical Escherichia coli isolates in Southeast Austria, 1998–2013 A. Badura, G. Feierl, G. Pregartner,

Active surveillance of antibiotic resistance prevalence in urinary tract and skin infections in the outpatient setting A. Kronenberg, S. Koenig, S. Droz,

Abstracts Clinical Microbiology and Infection

Modelling during an emergency: the 2009 H1N1 influenza pandemic

New oral cephalosporins in pediatric community-acquired infections

A. Manzur, F. Gudiol Clinical Microbiology and Infection

Quantitative real-time PCR and the (1 → 3)-β-d-glucan assay for differentiation between Pneumocystis jirovecii pneumonia and colonization Y. Matsumura,

B.A. Cunha Clinical Microbiology and Infection

Susceptibility of multi-drug-resistant Pseudomonas aeruginosa in intensive care units: results from the European MYSTIC study group† H. Goossens Clinical.

J.L. Balcázar Clinical Microbiology and Infection

G.C. Schito Clinical Microbiology and Infection

Impact of antibiotic restrictions: the patient's perspective

CMI readers' survey Clinical Microbiology and Infection

The future of diagnostic bacteriology

Presentation transcript:

High prevalence of mutators among Enterobacter cloacae nosocomial isolates and their association with antimicrobial resistance and repetitive detection A. Matsushima, S. Takakura, N. Fujihara, T. Saito, Y. Ito, Y. Iinuma, S. Ichiyama Clinical Microbiology and Infection Volume 16, Issue 9, Pages 1488-1493 (September 2010) DOI: 10.1111/j.1469-0691.2010.03145.x Copyright © 2010 European Society of Clinical Infectious Diseases Terms and Conditions

FIG. 1 Distribution of the mutation frequencies of 59 Enterobacter cloacae clinical isolates. Range, 5.8 × 10−9 to 8.0 × 10−6; median, 5.0 ×10−8. *Mutation frequency of E. cloacae ATCC 13047 (8.0 ×10−9). **Mutation frequency of Escherichia coli ATCC 25922 (1.7 ×10−8). Clinical Microbiology and Infection 2010 16, 1488-1493DOI: (10.1111/j.1469-0691.2010.03145.x) Copyright © 2010 European Society of Clinical Infectious Diseases Terms and Conditions

FIG. 2 Distribution of the mutation frequencies within the clonal groups and singletons. Filled circles: strong mutators. Open circles: weak mutators. Crosses: non-mutators. Clinical Microbiology and Infection 2010 16, 1488-1493DOI: (10.1111/j.1469-0691.2010.03145.x) Copyright © 2010 European Society of Clinical Infectious Diseases Terms and Conditions