Interference of Kv4 in dorsal neurons (DN1s) does not significantly regulate sleep onset. Interference of Kv4 in dorsal neurons (DN1s) does not significantly.

Slides:

Advertisements

Similar presentations

(A) Schematic illustration of the experimental design for the analysis of the RNase activity of MARF1 in oocytes by mutating the conserved D272 residue.

Advertisements

Body weight at harvest (g) Left kidney:body weight ratio (g/kg)

Volume 60, Issue 4, Pages (November 2008)

Fig. 5. Circulating PPi concentration does not correlate with severity of calcification phenotype in mice. Circulating PPi concentration does not correlate.

Volume 14, Issue 8, Pages (April 2004)

Quantification of the significantly changed metabolites.

Surface renderings of the brain activation showing significant activation in the general mixed design ANOVA for the interaction between all three factors,

by Xitong Liang, Timothy E. Holy, and Paul H. Taghert

Volume 23, Issue 3, Pages (February 2013)

MN-enriched miRNAs are depleted temporally in ALS rodent model and human patient spinal cord. MN-enriched miRNAs are depleted temporally in ALS rodent.

Fig. 5 Local gel scaffold for T cell memory response.

The Drosophila Clock Neuron Network Features Diverse Coupling Modes and Requires Network-wide Coherence for Robust Circadian Rhythms Zepeng Yao, Amelia.

Activation of PBN and CeA by illuminating the hindpaw after PNI

Volume 74, Issue 4, Pages (May 2012)

Yong Zhang, Patrick Emery Neuron

Pallavi Lamba, Diana Bilodeau-Wentworth, Patrick Emery, Yong Zhang

A Conserved Circadian Function for the Neurofibromatosis 1 Gene

GlyR activation modulates its diffusion properties around active synapses. GlyR activation modulates its diffusion properties around active synapses. A,

Volume 22, Issue 19, Pages (October 2012)

Comparison of fecal metabolite concentrations in breast-fed (BF, green), standard formula-fed (FF, red), and B. lactis-supplemented formula-fed (FF + B.

Fig. 1 KCC2 down-regulation is prevented in sortilin-deficient mice.

Plotted are stimulus-response curves for the flare size at feet (A) (filled symbols) and thighs (B) (open symbols) and the respective flux values (feet,

Decreasing sleep levels using dTRPA1-based reversible activation of dopaminergic neurons reversibly decreases egg output. Decreasing sleep levels using.

Sleep deprivation by caffeine and mechanical disturbance of w1118 flies results in a decrease in egg output. Sleep deprivation by caffeine andmechanical.

CRISPRa sgRNA multiplexing for synergistic or coordinated control of gene expression. CRISPRa sgRNA multiplexing for synergistic or coordinated control.

CRISPRa induction of Bdnf transcript variants I and IV in primary rat hippocampal neurons. CRISPRa induction of Bdnf transcript variants I and IV in primary.

The complexity as well as the total dendritic length of ApoE-deficient adult-born granule cells are significantly reduced. The complexity as well as the.

The complexity and the total dendritic length of ApoE4 adult-born granule cells are significantly reduced. The complexity and the total dendritic length.

CK2 phosphorylates mammalian FMRP S499.

Presynaptic OSN GABA receptors accelerate behavioral responses to odor pulse termination. Presynaptic OSN GABA receptors accelerate behavioral responses.

Marginal means (±s.e.m.) of temperatures for four tissues in 13 king penguins while fasting in water. Marginal means (±s.e.m.) of temperatures for four.

Increased phosphorylation of Akt, Girdin S1416, and NR2B of NMDA receptor in the hippocampus of mouse after fear conditioning. Increased phosphorylation.

Peli1 levels are reduced in bid−/− microglia upon LPS stimulation.

Phosphorylated CREB levels were assessed in the hippocampus at 20 min after cue and contextual fear conditioning. Phosphorylated CREB levels were assessed.

Loss of ATF3 function modestly reduces axonal regeneration following sciatic nerve crush. Loss of ATF3 function modestly reduces axonal regeneration following.

Electrically evoked dopamine transients and regulation of dopamine signals by firing frequency in wild-type and triple-synuclein-null mutant mice measured.

Loss of Nrf2 function in vivo increased cortical damage after permanent focal ischemia. Loss of Nrf2 function in vivo increased cortical damage after permanent.

Mice fed GP-SPI diet show improved fasting glucose and oral glucose tolerance. Mice fed GP-SPI diet show improved fasting glucose and oral glucose tolerance.

Chronic SSRI treatment rescued lOFC hyperactivity in QNP-treated mice.

Gene delivery of ChABC leads to improved sensorimotor function and spinal conduction following spinal contusion. Gene delivery of ChABC leads to improved.

Tactile allodynia with activation of dorsal horn neuron in atopy model mice. Tactile allodynia with activation of dorsal horn neuron in atopy model mice.

Knockdown of ZBP1 in hippocampal neurons decreases dendritic branching

Diaphanous is required presynaptically for normal synaptic growth.

PTZ-induced neuronal activity visualized by IEGs

Effect of PPARγ agonist on Aβ phagocytosis in primary microglia.

Transgenic expression of mCREB or CREB produces opposite effects in the learned helplessness model of depression. Transgenic expression of mCREB or CREB.

Peripheral surgery regulates expression of astrocytic markers.

The developmental spine morphology changes predict decreased biochemical compartmentalization with age, while loss of FMRP subtly influences this in an.

PDL-coated beads induce the formation of functional presynaptic terminals within 24 h. PDL-coated beads induce the formation of functional presynaptic.

Fig. 4 Reconstitution of MCs in KitW-sh/W-sh mice increases IL-10+ Breg cells and suppresses the CHS response. Reconstitution of MCs in KitW-sh/W-sh mice.

CRISPRa induction of Bdnf mRNA increases spike and burst frequency in hippocampal neurons cultured on microelectrode arrays (MEAs). CRISPRa induction of.

Distribution of NE- and KCl-responsive precursor cells along the septotemporal axis of the hippocampus. Distribution of NE- and KCl-responsive precursor.

Mice with Ric-8b-deficient olfactory epithelium show impaired olfactory guided behavior. Mice with Ric-8b-deficient olfactory epithelium show impaired.

NPC-derived oligodendrocytes are maintained long term after cuprizone challenge. NPC-derived oligodendrocytes are maintained long term after cuprizone.

The repertoire of NPC-derived cells within the CC during cuprizone-induced demyelination. The repertoire of NPC-derived cells within the CC during cuprizone-induced.

MET-1 increases DRG neuron K+ currents.

FMRP S499 rephosphorylation kinetics after CX-4945 treatment and washout mirrors a known CK2 target. FMRP S499 rephosphorylation kinetics after CX-4945.

A, Hippocampal protein levels of IL-6 in LD and DD mice treated with PDTC, ASA, or saline controls. A, Hippocampal protein levels of IL-6 in LD and DD.

Cytokine expression in the ileum and colon.

Rate of current rundown through VDCC and NMDA receptor channels is reduced in gelsolin-deficient hippocampal neurons. Rate of current rundown through VDCC.

FKBP1b counters the age-related decrease in hippocampal MAP2 protein expression. FKBP1b counters the age-related decrease in hippocampal MAP2 protein expression.

At P23, dendritic spine density on L2/3 pyramidal cells in PirB−/− visual cortex is similar to that of PirB+/+. At P23, dendritic spine density on L2/3.

Optogenetically stimulated Aβ fibers induce pain-like behaviors after PNI. A, B, Withdrawal score by light (A) and paw withdrawal threshold by von Frey.

Quantification of TUNEL staining and OS length among the rab11a constructs. Quantification of TUNEL staining and OS length among the rab11a constructs.

SIRT1 deletion exacerbates premature lethality and synapse loss in tauP301S mice. SIRT1 deletion exacerbates premature lethality and synapse loss in tauP301S.

Neutralization of CSF1 and Ad5-HRG treatment.

Subodh Verma et al. BTS 2018;3:

ΔFosB regulates spike number in hippocampal CA1 neurons.

Volume 14, Issue 8, Pages (April 2004)

Volume 90, Issue 4, Pages (May 2016)

Presentation transcript:

Interference of Kv4 in dorsal neurons (DN1s) does not significantly regulate sleep onset. Interference of Kv4 in dorsal neurons (DN1s) does not significantly regulate sleep onset. A, B, Conventional sleep plots of controls (Clk4.1M-GAL4, UAS-DNKv4, and R18H11-GAL4; n = 27–32) and experimental flies (Clk4.1M>DNKv4 and R18H11>DNKv4; n = 30) in LD cycles. C, Quantification of sleep latency after lights-off. Mean ± SEM is shown. n.s., not significant. One-way ANOVAs followed by post hoc Tukey were performed. Data are compared by one-way ANOVAs followed by post hoc Tukey. Ge Feng et al. J. Neurosci. 2018;38:9059-9071 ©2018 by Society for Neuroscience