Transverse FLAIR (bottom row) and DIR (top row) sections of the supratentorial brain. Transverse FLAIR (bottom row) and DIR (top row) sections of the supratentorial.

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Transverse FLAIR (bottom row) and DIR (top row) sections of the supratentorial brain. Transverse FLAIR (bottom row) and DIR (top row) sections of the supratentorial brain. The inflammatory lesions have a more sharp delineated appearance on the DIR compared with the corresponding FLAIR images. Despite a minor contrast between lesions and the normal-appearing gray matter, DIR showed a high sensitivity in the detection of juxtacortical and mixed white matter-gray matter lesions (arrows). A differentiation between juxtacortical and mixed white matter-gray matter lesions is much easier on the DIR than on the FLAIR images. Regarding the periventricular white matter, the lesions are easier to identify on the DIR compared with the FLAIR images (open arrows). M.P. Wattjes et al. AJNR Am J Neuroradiol 2007;28:54-59 ©2007 by American Society of Neuroradiology