Fig. 5 Impaired colitis induction by LRH-1–deficient CD4+T cells.

Slides:

Advertisements

Similar presentations

Fig. 4 Altitudinal distributions of ice thickness change (m year−1) for the 650 glaciers. Altitudinal distributions of ice thickness change (m year−1)

Advertisements

Fig. 2 Transport properties of a BP transistor at low temperature.

Fig. 3 The electrical contact of direct-printed and reconfigured liquid metals. The electrical contact of direct-printed and reconfigured liquid metals.

Fig. 2 Global production, use, and fate of polymer resins, synthetic fibers, and additives (1950 to 2015; in million metric tons). Global production, use,

Fig. 2 CFD results. CFD results. Results of CFD simulations in horizontal (left column) and vertical (right column) cross-sections. All models oriented.

Vibrational spectra of medieval human bones (Leopoli-Cencelle, Italy)

Fig. 3 Oil, gas, and FP water variations with time.

Fig. 5 Thermal conductivity of n-type ZrCoBi-based half-Heuslers.

Fig. 1 Map of water stress and shale plays.

Fig. 1 Examples of experimental stimuli and behavioral performance.

Fig. 4 Resynthesized complex boronic acid derivatives based on different scaffolds on a millimole scale and corresponding yields. Resynthesized complex.

Fig. 6 Comparison of properties of water models.

Fig. 1 Mean and median RCR (Relative Citation Ratio) of Roadmap Epigenomics Program research articles for each year. Mean and median RCR (Relative Citation.

Fig. 2 Influence of the Roadmap Epigenomics Program on the field of epigenomics research. Influence of the Roadmap Epigenomics Program on the field of.

Fig. 2 Reference-fixing experiment, results.

Fig. 3 Swarm material properties.

Fig. 2 Average number of fake news shares (and 95% CIs) using the list of domains derived from (7). Average number of fake news shares (and 95% CIs) using.

Fig. 3 Glucose- and structure-dependent insulin release.

Fig. 1 Experimental apparatus used to train and test free-flying bees on their capacity to learn addition and subtraction. Experimental apparatus used.

Fig. 3 Rotation experiment, setup.

Fig. 1 Product lifetime distributions for the eight industrial use sectors plotted as log-normal probability distribution functions (PDF). Product lifetime.

Fig. 3 Gate voltage dependence of the areal iDMI and PMA.

Fig. 1 Distribution of total and fake news shares.

Fig. 6 Maternally derived type 2 CD4+T cells are enriched in NbM dam milk and are required for transfer of protection. Maternally derived type 2 CD4+T.

Fig. 4 Reconstitution of MCs in KitW-sh/W-sh mice increases IL-10+ Breg cells and suppresses the CHS response. Reconstitution of MCs in KitW-sh/W-sh mice.

Fig. 2 2D QWs of different propagation lengths.

Electronic structure of the oligomer (n = 8) at the UB3LYP/6-31G

Fig. 6 WPS imaging of different chemical components in living cells.

Fig. 4 DFT ωB97x/def2-TZVPP atomic charges on the sulfur atom of substituted thioaldehyde and AIMNet prediction with a different number of iterative passes.

Fig. 3 ET dynamics on the control and treatment watersheds during the pretreatment and treatment periods. ET dynamics on the control and treatment watersheds.

Fig. 1 Histograms of the number of first messages received by men and women in each of our four cities. Histograms of the number of first messages received.

Fig. 5 Schematic phase diagrams of Ising spin systems and Mott transition systems. Schematic phase diagrams of Ising spin systems and Mott transition systems.

Fig. 4 OER performance of ACoO3 (A = Ca, Sr) in alkaline solutions with different pH. OER performance of ACoO3 (A = Ca, Sr) in alkaline solutions with.

Fig. 1 Average contribution (million metric tons) of seafood-producing sectors, 2009–2014. Average contribution (million metric tons) of seafood-producing.

Fig. 5 A holistic formula TNTL targeting SBP2 in ATMs improved insulin resistance in obese mice. A holistic formula TNTL targeting SBP2 in ATMs improved.

Fig. 1 Cross-sectional images of He-implanted V/Cu/V samples.

Fig. 3 Production of protein and Fe(II) at the end of growth correlated with increasing concentrations of ferrihydrite in the media that contained 0.2.

Fig. 2 Loss of SBP2 induced inflammations in metabolically activated ATMs and inflammasome-associated IL-1β production. Loss of SBP2 induced inflammations.

Fig. 2 Schematic drawings of Göbekli Tepe skulls.

Fig. 2 NH3, NOx, SO2, and NMVOC emission changes triggered by the JJJ clean air policy. NH3, NOx, SO2, and NMVOC emission changes triggered by the JJJ.

Fig. 1 Size fractions of MPPs in different fertilizers.

Fig. 4 Overexpression of SBP2 improved insulin sensitivity and suppressed adipogenesis in obese mice. Overexpression of SBP2 improved insulin sensitivity.

Fig. 4 Dox-CBD-SA treatment shows reduced toxicity.

Fig. 2 Sampling. Sampling. (A) Extant stratigraphic section. Zenithal (B) and frontal (C) views of the flowstone capping the excavated deposit. The rectangle.

Fig. 1 Global occurrences of hydraulic fracturing–induced seismicity and potential models. Global occurrences of hydraulic fracturing–induced seismicity.

Fig. 2 Top 10 countries, ecoregions, conservation hotspots, and KBAs with the largest area of restoration hotspots. Top 10 countries, ecoregions, conservation.

Fig. 5 Global patterns in total fisheries catches from over more than 50 years as seen in three example stanzas. Global patterns in total fisheries catches.

Fig. 5 Comparison of the liquid products generated from photocatalytic CO2 reduction reactions (CO2RR) and CO reduction reactions (CORR) on two catalysts.

Schematic of the proposed brain-controlled assistive hearing device

Fig. 1 Location of the Jirzankal Cemetery.

Fig. 4 CO2 emission changes triggered by the JJJ clean air policy.

Fig. 2 Simulations of possible doping positions and band structures.

Fig. 2 Mean field results. Mean field results. (A) Solutions P(x) to Eq. 4 for a range of T and wc = (B) Modulus ∣pk∣ of order parameters versus.

Fig. 3 Comparisons of NDVI trends over the globally vegetated areas from 1982 to Comparisons of NDVI trends over the globally vegetated areas from.

Experimenter gender and replicability in science

Fig. 1 Schematic depiction of a paradigm for rapid and guided discovery of materials through iterative combination of ML with HiTp experimentation. Schematic.

Fig. 4 Spatial mapping of the distribution and intensity of industrial fishing catch. Spatial mapping of the distribution and intensity of industrial fishing.

Fig. 4 Single-particle contact angle measurements.

Fig. 2 Supraballs and films from binary SPs.

Fig. 3 Performance of the generative model G, with and without stack-augmented memory. Performance of the generative model G, with and without stack-augmented.

Fig. 4 Behavior of resistance peak near density nm = 5.

Fig. 2 Comparison between the different reflective metasurface proposals when θi = 0° and θr = 70°. Comparison between the different reflective metasurface.

Fig. 1 Overview of amber clast with synchrotron x-ray μCT image of articulated snake skeleton (DIP-S-0907). Overview of amber clast with synchrotron x-ray.

Fig. 4 Effects of individual picosecond and microsecond pulses.

Fig. 3 Calculated electronic structure of ZrCoBi.

Fig. 1 Attractive interaction between a doublon and a holon due to antiferromagnetic exchange interactions in half-filled 2D Mott insulators. Attractive.

Fig. 2 Cxxc1 deficiency restricts T cell–mediated autoimmunity and increases sensitivity to C. rodentium infection. Cxxc1 deficiency restricts T cell–mediated.

Fig. 5 CD19-tPSMA(N9del) CAR T cell numbers in mouse and human.

Fig. 1 TH17 cell differentiation was severely impaired in Cxxc1-deficient mice. TH17 cell differentiation was severely impaired in Cxxc1-deficient mice.

Cxxc1-deficient TH17 cells exhibit a Treg cell–like expression profile

Presentation transcript:

Fig. 5 Impaired colitis induction by LRH-1–deficient CD4+T cells. Impaired colitis induction by LRH-1–deficient CD4+T cells. (A) Scheme of transfer colitis induction in Rag1−/− recipient mice. (B) Colitis-induced loss of body weight (L2/L2 donor, n = 14; cKO donor, n = 9). (C to E) Representative histologies of colon samples from untreated Rag1−/− recipient mice (C) or after transfer of naïve L2/L2 (D) or cKO T cells (E). Top panels: Lower magnification. Bottom panels: Higher magnification. Scale bars, 150 μm. (F and G) Repopulation of spleen (F) or mesenteric lymph node (mLN) (G) by naïve L2/L2 or cKO T cells. (H to J) mRNA expression levels of the proinflammatory cytokines tumor necrosis factor–α (H), IL-1β (I), and IFN-γ (J) in colon samples or control recipients or recipients transferred with L2/L2 or cKO T cells. Mean ± SD and individual data points of n = 9 to 14 mice are shown. *P < 0.05, **P < 0.01, and ***P < 0.001. Carina Seitz et al. Sci Adv 2019;5:eaav9732 Copyright © 2019 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution NonCommercial License 4.0 (CC BY-NC).