Trained immunity induction of glycolysis.

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Presentation transcript:

Trained immunity induction of glycolysis. Trained immunity induction of glycolysis. Cells were trained for 2 h (2hr-T), 4 h (4hr-T), or 24 h (24hr-T) with RPMI (negative control), β-glucan, BCG, or oxLDL and rested for 24 h (24hr-R), 3 days (3d-R), or 6 days (6d-R). The level of lactate production in the supernatants was measured before restimulation (n = 6; *, P < 0.05 compared to the RPMI control; **, P < 0.01 compared to the RPMI control; ns, not significant). Siroon Bekkering et al. Clin. Vaccine Immunol. 2016; doi:10.1128/CVI.00349-16