Schematics of mechanisms behind compartmentalization of RBPs on microtubules. Schematics of mechanisms behind compartmentalization of RBPs on microtubules.

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Schematics of mechanisms behind compartmentalization of RBPs on microtubules. Schematics of mechanisms behind compartmentalization of RBPs on microtubules. A, Confining RBPs on microtubules leads to the formation of RNA-rich compartments. B, Molecular interactions accounting for the formation of mRNA granules on microtubules. RRMs, RNA-Recognition Motifs; LCD, Low Complexity Domains. C, The miscibility of liquid-like compartments depends on the interaction between coexisting RBPs. Alexandre Maucuer et al. J Cell Sci 2018;131:jcs214692 © 2018. Published by The Company of Biologists Ltd