Illustration of model 1, with CFQ-R total score as the outcome.

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Presentation transcript:

Illustration of model 1, with CFQ-R total score as the outcome. Illustration of model 1, with CFQ-R total score as the outcome. The manifest (=observed) variables FEV1, BMI, PWC and lgG (reversed) are used as indicators of the latent variable medical status, and this latent variable is included as a mediator mediating the effects of the predictors Groups 1–3, age and the Groups 1–3×age interaction effect on CFQ-R total score. The effects are adjusted for the effects of sex, having a partner or not and level of education. The parameter values are standardised regression coefficients. †p<0.10, *p<0.05, **p<0.001. BMI, body mass index; CFQ-R, Cystic Fibrosis Questionnaire-Revised; FEV1, forced expiratory volume in 1 s; lgG, immunoglobulin G; PWC, physical working capacity. Lena Backström-Eriksson et al. BMJ Open Resp Res 2016;3:e000141 ©2016 by British Thoracic Society