Accuracy of carotid Doppler peak frequency analysis: Results determined by receiver operating characteristic curves and likelihood ratios K.W. Johnston,

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Presentation transcript:

Accuracy of carotid Doppler peak frequency analysis: Results determined by receiver operating characteristic curves and likelihood ratios K.W. Johnston, M.D., R.B. Haynes, M.D., Y. Douville, M.D., M.E. Lally, M.D., P.M. Brown, M.D., R.S.C. Cobbold, Ph.D. Journal of Vascular Surgery Volume 2, Issue 4, Pages 515-523 (July 1985) DOI: 10.1016/0741-5214(85)90002-3 Copyright © 1985 Society for Vascular Surgery and North American Chapter, International Society for Cardiovascular Surgery Terms and Conditions

Fig. 1 Plot of %IC as measured by arteriography vs. maximal Doppler PF recorded from internal carotid artery with 4 MHz probe. Results for arterial occlusions are not plotted in this figure but have been included in all calculations. Note variation in diameter of nonstenotic internal carotid artery bulb. Journal of Vascular Surgery 1985 2, 515-523DOI: (10.1016/0741-5214(85)90002-3) Copyright © 1985 Society for Vascular Surgery and North American Chapter, International Society for Cardiovascular Surgery Terms and Conditions

Fig. 2 ROC curves. Threshold values of PF have been incremented in 0.1 kHz steps. Arteriogram was considered positive based on following different criteria: A, >60% stenosis, B, >50% stenosis, C, >40% stenosis, and D, >30% stenosis. Journal of Vascular Surgery 1985 2, 515-523DOI: (10.1016/0741-5214(85)90002-3) Copyright © 1985 Society for Vascular Surgery and North American Chapter, International Society for Cardiovascular Surgery Terms and Conditions

Fig. 3 Plots of relationship between pretest and posttest probabilities of carotid disease for different ranges of PF. Likelihood ratios from Table III have been used in these calculations. Arteriogram was considered positive based on following different criteria: A, >60% stenosis, B, >50% stenosis, C, >40% stenosis, and D, >30% stenosis. Journal of Vascular Surgery 1985 2, 515-523DOI: (10.1016/0741-5214(85)90002-3) Copyright © 1985 Society for Vascular Surgery and North American Chapter, International Society for Cardiovascular Surgery Terms and Conditions

Fig. 4 From this example probability that carotid stenosis >50% exists can be determined from measured PF and clinically estimated pretest probability of carotid stenosis. Journal of Vascular Surgery 1985 2, 515-523DOI: (10.1016/0741-5214(85)90002-3) Copyright © 1985 Society for Vascular Surgery and North American Chapter, International Society for Cardiovascular Surgery Terms and Conditions