Reduced inotropic support after aprotinin therapy during pediatric cardiac operations  Carl F Wippermann, MD, Franz X Schmid, MD, Balthasar Eberle, MD,

Slides:



Advertisements
Similar presentations
Impact of cardiac surgery using cardiopulmonary bypass on course of chronic lymphatic leukemia: a case-control study Evgenij V Potapov, MD, Heinz R Zurbrügg,
Advertisements

The effect of cardiotomy suction on the brain injury marker S100β after cardiopulmonary bypass  Russell E Anderson, MD, PhD, Lars-Olof Hansson, MD, PhD,
Stress-Dose Corticosteroid Versus Placebo in Neonatal Cardiac Operations: A Randomized Controlled Trial  Pertti K. Suominen, MD, PhD, Juho Keski-Nisula,
Postconditioning the Human Heart with Adenosine in Heart Valve Replacement Surgery  Zhen-Xiao Jin, MD, Jing-Jun Zhou, PhD, Mei Xin, MS, Dao-Rong Peng,
Antithrombin Administration in Patients With Low Antithrombin Values After Cardiac Surgery: A Randomized Controlled Trial  Domenico Paparella, MD, Crescenzia.
Postoperative use of aprotinin in cardiac operations: An alternative to its prophylactic use  Sertaç Ciçek, MD*, Ufuk Demirkiliç, MD, Ertugrul Özal, MD,
Phosphorylcholine Coating May Limit Thrombin Formation During High-Risk Cardiac Surgery: A Randomized Controlled Trial  Federico Pappalardo, MD, Patrizia.
Cumulative Corticosteroid Exposure and Infection Risk After Complex Pediatric Cardiac Surgery  Christopher W. Mastropietro, MD, Renee Barrett, MD, Maria.
Long-Term Outcome of Coronary Artery Bypass Grafting in Patients With Left Ventricular Dysfunction  Paolo Nardi, MD, PhD, Antonio Pellegrino, MD, Antonio.
Risk-Adjusted Prolonged Length of Stay as an Alternative Outcome Measure for Pediatric Congenital Cardiac Surgery  Ming Liu, MS, MA, Charlotte M. Druschel,
Treatment of a persistent postoperative chylothorax with somatostatin
Warfarin Cessation Before Cardiopulmonary Bypass: Lessons Learned from a Randomized Controlled Trial of Oral Vitamin K  Richard P. Whitlock, MD, Mark.
Effect of hemofiltrated whole blood pump priming on hemodynamics and respiratory function after the arterial switch operation in neonates  Mitsugi Nagashima,
Prospective, Randomized, Double-Blind Study of High-Dose Aprotinin in Pediatric Cardiac Operations  Michael J Davies, FRCS, Alison Allen, BScHons, Henry.
James L Zellner, MD, Scott B Kribbs, BS, B
Influence of perioperative factors on outcomes in children younger than 18 months after repair of tetralogy of Fallot  Umesh Dyamenahalli, MD, Brian W.
Cardiac Operations in Solid-Organ Transplant Recipients
Leukocyte depletion during cardiac operation: a new approach through the venous bypass circuit  Y.John Gu, MD, PhD, A.J de Vries, MD, Paulien Vos, Piet.
Sivelestat Attenuates Lung Injury in Surgery for Congenital Heart Disease With Pulmonary Hypertension  Norikazu Nomura, MD, PhD, Miki Asano, MD, PhD,
Metabolic and Hemodynamic Effects of High-Dose Insulin Treatment in Aortic Valve and Coronary Surgery  Juha K. Koskenkari, MD, Päivi K. Kaukoranta, MD,
Chest Reexploration in the Intensive Care Unit After Cardiac Surgery: A Safe Alternative to Returning to the Operating Theater  Charalambos P. Charalambous,
François Dagenais, MD, L.Conrad Pelletier, MD, Michel Carrier, MD 
Temporary Atrial Electrode for the Treatment of Supraventricular Tachycardia After Cardiac Operations  Hormoz Mehmanesh, Rüdiger Lange, Siegfried Hagl 
Use of an Adjustable Tourniquet to Reverse Cyanosis in the Newborn Pig
Aprotinin in pediatric cardiac operations: a benefit in complex malformations and with high-dose regimen only  Thierry P Carrel, MD, Mike Schwanda, MD,
Magnesium-supplemented warm blood cardioplegia in patients undergoing coronary artery revascularization  Mark Yeatman, Massimo Caputo, MD, Pradeep Narayan,
Susanne Lison, MD, Michael Spannagl, MD, PhD, Wulf Dietrich, MD, PhD 
Cardiac pacing in premature infants and neonates: steroid eluting leads and automatic output adaptation  Franz X Schmid, MD, Bernd Nowak, MD, Christoph.
An Analysis of Oxygen Consumption and Oxygen Delivery in Euthermic Infants After Cardiopulmonary Bypass With Modified Ultrafiltration  Jia Li, MD, PhD,
Central venous catheter use in low-risk coronary artery bypass grafting  Robert D Stewart, MD, Triffin Psyhojos, MD, Stephen J Lahey, MD, Sidney Levitsky,
Initial Clinical Experience With the Symphony Heart Assist System
Farkas Vánky, MD, Mats Broquist, MD, PhD, Rolf Svedjeholm, MD, PhD 
Damien J. LaPar, MD, MS, James M. Isbell, MD, MSCI, Daniel P
Stress-Dose Corticosteroid Versus Placebo in Neonatal Cardiac Operations: A Randomized Controlled Trial  Pertti K. Suominen, MD, PhD, Juho Keski-Nisula,
John S. Ikonomidis, MD, PhD, Ebony J
Surgical Dilemmas: Diagnosis and Treatment of Atrial Plasmacytoma
Torsten Doenst, MD, Wolfgang Bothe, MD, Friedhelm Beyersdorf, MD 
Early postoperative body temperature and developmental outcome after open heart surgery in infants  Serena M Cottrell, MRCPCH, Kevin P Morris, MD, Paul.
Antithrombin Administration in Patients With Low Antithrombin Values After Cardiac Surgery: A Randomized Controlled Trial  Domenico Paparella, MD, Crescenzia.
Adenosine instead of supranormal potassium in cardioplegia: It is safe, efficient, and reduces the incidence of postoperative atrial fibrillation. A randomized.
Biventricular repair in neonates with hypoplastic left heart complex
Repair of aortic coarctation in patients more than 50 years of age
Russel Hirsch, Catherine L. Dent, Mary K. Wood, Charles B
Editorial Board, January 2010
Sarah C. Huen, MD, Chirag R. Parikh, MD, PhD 
Anticoagulation with bivalirudin during cardiopulmonary bypass in cardiac surgery  Julio C Vasquez, MD, Anna Vichiendilokkul, PharmD, Syed Mahmood, MD,
Surgical-Interventional Hybrid Concept in a Newborn With Borderline Left Heart  Stefan Rupp, MD, Josef Thul, MD, Kerstin Gummel, MD, Markus Khalil, MD,
Time course of proinflammatory and anti-inflammatory responses after cardiac operation: monocyte HLA-DR expression  Y.John Gu, MD, PhD, Willem van Oeveren,
Adjustable tourniquet to manipulate pulmonary blood flow after Norwood operations  Franz X Schmid, MD, Christoph Kampmann, MD, Wlodimierz Kuroczynski,
Tachyarrhythmias and triggering factors for atrial fibrillation after coronary artery bypass operations  Lena Jidéus, MD, Per Blomström, MD, PhD, Leif.
Preoperative risk factors for right ventricular failure after implantable left ventricular assist device insertion  Kiyotaka Fukamachi, MD, PhD, Patrick.
Aprotinin Enhances the Endogenous Release of Interleukin-10 After Cardiac Operations  Gary E Hill, Robert P Diego, Alfred H Stammers, Suzanne M Huffman,
Comparison of epsilon aminocaproic acid and low-dose aprotinin in cardiopulmonary bypass: efficiency, safety and cost  Michael J Ray, PhD, Mark F O’Brien 
Aprotinin is Not Associated With Postoperative Renal Impairment After Primary Coronary Surgery  Gabriella Lindvall, MD, Ulrik Sartipy, MD, PhD, Torbjörn.
Postoperatively administered aprotinin or epsilon aminocaproic acid after cardiopulmonary bypass has limited benefit  Michael J Ray, PhD, Majella M Hales,
Sérgio A de Oliveira, MD  The Annals of Thoracic Surgery 
Kirk R Kanter, MD, Robert N Vincent, MD, Anthony A Raviele, MD 
Inhaled iloprost in patients with chronic thromboembolic pulmonary hypertension: effects before and after pulmonary thromboendarterectomy  Thorsten Kramm,
Prospective Validation of a Novel Vasoactive-Ventilation-Renal Score as a Predictor of Outcomes After Pediatric Cardiac Surgery  Kyle G. Miletic, MD,
Treatment of left atrial dissection after mitral repair: internal drainage  Michele Genoni, MD, Rolf Jenni, MD, Edith R Schmid, MD, Paul R Vogt, MD, Marko.
Factors influencing intensive care unit length of stay after surgery for acute aortic dissection type A  Daniel Hoefer, MD, Elfriede Ruttmann, MD, Markus.
Fibrinolysis-adjusted perioperative low-dose aprotinin reduces blood loss in bypass operations  Martin Misfeld, MD, Sven Dubbert, Sawas Eleftheriadis,
The Impact of New Technology on Cardiothoracic Surgical Practice
Reduced Cytokines Release and Myocardial Damage in Coronary Artery Bypass Patients Due to L-Arginine Cardioplegia Supplementation  Luisa Colagrande, MD,
Robert J Frumento, MS, MPH, Catherine M
Left Ventricular End-Diastolic Pressure Predicts Survival in Coronary Artery Bypass Graft Surgery Patients  Jeevan Nagendran, MD, PhD, Colleen M. Norris,
Short Operation Time: An Important Element to Reduce Operative Invasiveness in Pediatric Cardiac Surgery  Makoto Ando, MD, Yukihiro Takahashi, MD, Toshio.
On-pump versus off-pump coronary artery bypass grafting: impact on postoperative renal failure requiring renal replacement therapy  Jan Bucerius, MD,
Intravenous milrinone in cardiac surgery
High-Dose ϵ-Aminocaproic Acid Versus Aprotinin: Antifibrinolytic Efficacy in First-Time Coronary Operations  Balthasar Eberle, Eckhard Mayer, Gerhard.
Presentation transcript:

Reduced inotropic support after aprotinin therapy during pediatric cardiac operations  Carl F Wippermann, MD, Franz X Schmid, MD, Balthasar Eberle, MD, Ralf G Huth, MD, Christoph Kampmann, MD, Dietmar Schranz, MD, Helmut Oelert, MD, PhD  The Annals of Thoracic Surgery  Volume 67, Issue 1, Pages 173-176 (January 1999) DOI: 10.1016/S0003-4975(98)00974-6

Fig 1 Left atrial pressure (LAP), shortening fraction, cumulative epinephrine dose [μg/kg], and cumulative enoximone dose [mg/kg] on arrival at the intensive care unit (ICU) 6, 12, 24, and 48 hours after weaning from bypass in the aprotinin group (closed circles) and placebo group (open triangles). There were no significant differences between the two groups in LAP and the cumulative epinephrine dose. The shortening fraction in the placebo group was reduced immediately postoperatively but did not reach significance. With the exception of 6 hours after bypass the placebo group received more enoximone. Values are shown as mean ± standard deviation. (ns = not significant; ∗ p < 0.05). The Annals of Thoracic Surgery 1999 67, 173-176DOI: (10.1016/S0003-4975(98)00974-6)