The role of peripheral afferents in persistent inguinal postherniorrhaphy pain: a randomized, double-blind, placebo-controlled, crossover trial of ultrasound-guided.

Slides:

Advertisements

Similar presentations

Chewing gum for the treatment of postoperative nausea and vomiting: a pilot randomized controlled trial J.N. Darvall, M Handscombe, K Leslie British.

Advertisements

Paravertebral block in paediatric abdominal surgery'a systematic review and meta- analysis of randomized trials E.A. Page, K.L. Taylor British Journal.

Comparison between ultrasound-guided transversus abdominis plane and conventional ilioinguinal/iliohypogastric nerve blocks for day-case open inguinal.

Effect of high-dose preoperative methylprednisolone on recovery after total hip arthroplasty: a randomized, double-blind, placebo-controlled trial T.H.

J. M. C. Strid, A. R. Sauter, K Ullensvang, M. N

When fasted is not empty: a retrospective cohort study of gastric content in fasted surgical patients† P Van de Putte, L Vernieuwe, A Jerjir, L Verschueren,

Addition of transversus thoracic muscle plane block to pectoral nerves block provides more effective perioperative pain relief than pectoral nerves block.

Effects of maintaining a remifentanil infusion on the recovery profiles during emergence from anaesthesia and tracheal extubation J.-S. Nho, S.-Y. Lee,

Extrafascial injection for interscalene brachial plexus block reduces respiratory complications compared with a conventional intrafascial injection: a.

Bispectral index-guided induction of general anaesthesia in patients undergoing major abdominal surgery using propofol or etomidate: a double-blind, randomized,

Dexmedetomidine vs propofol-remifentanil conscious sedation for awake craniotomy: a prospective randomized controlled trial† ‡ N Goettel, S Bharadwaj,

Analgesic efficacy of bilateral continuous transversus abdominis plane blocks using an oblique subcostal approach in patients undergoing laparotomy for.

Type of anaesthesia and patient quality of recovery: a randomized trial comparing propofol–remifentanil total i.v. anaesthesia with desflurane anaesthesia

Lidocaine use in ultrasound-guided femoral nerve block: what is the minimum effective anaesthetic concentration (MEAC90)?† A.M. Taha, A.M. Abd-Elmaksoud

Effect of adductor canal block on pain in patients with severe pain after total knee arthroplasty: a randomized study with individual patient analysis

K.-Y. Ho, W Tay, M.-C. Yeo, H Liu, S.-J. Yeo, S.-L. Chia, N.-N. Lo

Prospective randomized observer-blinded study comparing the analgesic efficacy of ultrasound-guided rectus sheath block and local anaesthetic infiltration.

Effect of combining tramadol and morphine in adult surgical patients: a systematic review and meta-analysis of randomized trials V. Martinez, L. Guichard,

Tapentadol potentiates descending pain inhibition in chronic pain patients with diabetic polyneuropathy M. Niesters, P.L. Proto, L. Aarts, E.Y. Sarton,

Cost-effectiveness of a systematic e-assessed follow-up of postoperative recovery after day surgery: a multicentre randomized trial K. Dahlberg, A. Philipsson,

I.-K. Song, H.-J. Kim, J.-H. Lee, E.-H. Kim, J.-T. Kim, H.-S. Kim

A comparison of the analgesic efficacy and side-effects of paravertebral vs epidural blockade for thoracotomy—a systematic review and meta-analysis of.

Differential effects of lidocaine and remifentanil on response to the tracheal tube during emergence from general anaesthesia J.H. Lee, B.-N. Koo, J.-J.

Ultrasound-guided radial artery cannulation in adult and paediatric populations: a systematic review and meta-analysis Leigh White, Alice Halpin, Marianne.

Does the prophylactic administration of magnesium sulphate to patients undergoing thoracotomy prevent postoperative supraventricular arrhythmias? A randomized.

Comparison between ultrasound-guided supraclavicular and infraclavicular approaches for subclavian venous catheterization in children'a randomized trial

T. Ledowski, J. Burke, J. Hruby British Journal of Anaesthesia

Influence of ketamine and morphine on descending pain modulation in chronic pain patients: a randomized placebo-controlled cross-over proof-of-concept.

Anticipating guidelines for ultrasound-guided arterial catheterization

Randomized, double-blind comparison of patient-controlled epidural infusion vs nurse- administered epidural infusion for postoperative analgesia in patients.

Complete heart block during central venous catheter placement in a patient with pre- existing left bundle branch block D Unnikrishnan, N Idris, N Varshneya

Intraoperative naloxone reduces remifentanil-induced postoperative hyperalgesia but not pain: a randomized controlled trial C.-H. Koo, S. Yoon, B.-R.

Sumatriptan improves postoperative quality of recovery and reduces postcraniotomy headache after cranial nerve decompression L. Venkatraghavan, L. Li,

Preoperative butorphanol and flurbiprofen axetil therapy attenuates remifentanil-induced hyperalgesia after laparoscopic gynaecological surgery: a randomized.

Efficacy of intravenous magnesium in neuropathic pain

Ultrasound-guided percutaneous cryoneurolysis for treatment of acute pain: could cryoanalgesia replace continuous peripheral nerve blocks? B.M. Ilfeld,

T. Saranteas, I. Koliantzaki British Journal of Anaesthesia

Epidural analgesia compared with peripheral nerve blockade after major knee surgery: a systematic review and meta-analysis of randomized trials S.J.

J. Lillesø, N.A. Hammer, J.L. Pedersen, H. Kehlet

K. Wildgaard, T. K. Ringsted, H. J. Hansen, R. H. Petersen, M. U

I.V. paracetamol as an adjunct to patient-controlled epidural analgesia with levobupivacaine and fentanyl in labour: a randomized controlled study K.

Randomized, Double-Blind, Placebo-Controlled Trial of Oral Docusate in the Management of Constipation in Hospice Patients Yoko Tarumi, MD, Mitchell P.

Double-blind, randomized, placebo-controlled trial comparing rofecoxib with dexketoprofen trometamol in surgical dentistry Jackson I.D. , Heidemann B.H.

E.K. Aasvang, M.U. Werner, H. Kehlet British Journal of Anaesthesia

Impact of balanced tetrastarch raw material on perioperative blood loss: a randomized double blind controlled trial† A Joosten, R Tircoveanu, S Arend,

D. Belavy, P.J. Cowlishaw, M. Howes, F. Phillips

Lung recruitment and positive airway pressure before extubation does not improve oxygenation in the post-anaesthesia care unit: a randomized clinical.

U. Eichenberger, C. Giani, S. Petersen-Felix, T. Graven-Nielsen, L

Recovery after total intravenous general anaesthesia or spinal anaesthesia for total knee arthroplasty: a randomized trial† A Harsten, H Kehlet, S Toksvig-Larsen

Postoperative pain relief after total hip arthroplasty: a randomized, double-blind comparison between intrathecal morphine and local infiltration analgesia

Spinal analgesia for laparoscopic colonic resection using an enhanced recovery after surgery programme: better analgesia, but no benefits on postoperative.

K. S. Khaw, S. W. Y. Lee, W. D. Ngan Kee, L. W. Law, T. K. Lau, F. F

Pain assessment in conscious healthy volunteers: a crossover study evaluating the analgesia/nociception index Q. Yan, H.Y. An, Y. Feng British Journal.

Corrigendum British Journal of Anaesthesia

Thoracic paravertebral blocks in abdominal surgery – a systematic review of randomized controlled trials K. El-Boghdadly, C. Madjdpour, K.J. Chin British.

Chewing gum for the treatment of postoperative nausea and vomiting: a pilot randomized controlled trial J.N. Darvall, M Handscombe, K Leslie British.

Efficacy of butylscopolamine for the treatment of catheter-related bladder discomfort: a prospective, randomized, placebo-controlled, double-blind study

J.B. Barbary, F. Remérand, J. Brilhault, M. Laffon, J. Fusciardi

Pregabalin has an opioid-sparing effect in elderly patients after cardiac surgery: a randomized placebo-controlled trial A. Pesonen, R. Suojaranta-Ylinen,

Characterization of peripheral and central sensitization after dorsal root ganglion intervention in patients with unilateral lumbosacral radicular pain:

Reduced hemidiaphragmatic paresis with extrafascial compared with conventional intrafascial tip placement for continuous interscalene brachial plexus.

Sodium bicarbonate does not prevent postoperative acute kidney injury after off-pump coronary revascularization: a double-blinded randomized controlled.

Postoperative analgesia with parecoxib, acetaminophen, and the combination of both: a randomized, double-blind, placebo-controlled trial in patients undergoing.

Oesophageal Doppler guided goal-directed haemodynamic therapy in thoracic surgery - a single centre randomized parallel-arm trial K.B. Kaufmann, L Stein,

A randomized trial of the effect of low dose epinephrine infusion in addition to tranexamic acid on blood loss during total hip arthroplasty Ø. Jans,

Regional anaesthesia to improve pain outcomes in paediatric surgical patients: a qualitative systematic review of randomized controlled trials S. Suresh,

Cricoid pressure force retention analysis using a simulator

Influence of head and neck position on ventilation using the air-Q® SP airway in anaesthetized paralysed patients: a prospective randomized crossover.

Effect of concentration of local anaesthetic solution on the ED50 of bupivacaine for supraclavicular brachial plexus block† P.K. Gupta, P.M. Hopkins

K. Ruetzler, G. Grubhofer, W. Schmid, D. Papp, S. Nabecker, D

Presentation transcript:

The role of peripheral afferents in persistent inguinal postherniorrhaphy pain: a randomized, double-blind, placebo-controlled, crossover trial of ultrasound-guided tender point blockade N Wijayasinghe, T.K. Ringsted, J.M. Bischoff, H Kehlet, M.U. Werner British Journal of Anaesthesia Volume 116, Issue 6, Pages 829-837 (June 2016) DOI: 10.1093/bja/aew071 Copyright © 2016 The Author(s) Terms and Conditions

Fig 1 Trial algorithm. Identical seven-day pain and sleep diaries (Questionnaire 1–3: only patients) were completed before Session 1, between Session 1 and 2, and, after Session 2. After baseline assessments of pain (summed pain intensity [P1/P3]: at rest [supine], on movement [supine to standing] and with pressure algometry [100 kPa]) and Sensory tests 1/3, an ultrasound-guided blockade with placebo or bupivacaine (Block 1/2) was performed. Thirty min (arrows) after induction of the blockade repeat assessments of pain (P2/P4) and Sensory tests 2/4 were performed. The sensory tests included thermal detection and pain thresholds, and, supra-threshold heat pain perception and pressure pain thresholds. British Journal of Anaesthesia 2016 116, 829-837DOI: (10.1093/bja/aew071) Copyright © 2016 The Author(s) Terms and Conditions

Fig 2 Ultrasound-guided tender point injection. RA+rectus abdominis muscle insertion and its aponeurosis. Yellow triangle at the top of the image represents the middle of the ultrasound probe, which is placed on the tender point. a: before injection b: during injection; visualization of spread of the solution (black area). British Journal of Anaesthesia 2016 116, 829-837DOI: (10.1093/bja/aew071) Copyright © 2016 The Author(s) Terms and Conditions

Fig 3 Patient flow through the trial (CONSORT diagram 2001). British Journal of Anaesthesia 2016 116, 829-837DOI: (10.1093/bja/aew071) Copyright © 2016 The Author(s) Terms and Conditions

Fig 4 Dot-line diagram presenting summed pain intensity difference (SPID) after placebo and bupivacaine injections for individual patients. SPID is expressed as a percentage and calculated as: ((SPIpre-injection–SPIpost-injection)/SPIpre-injection)×100. British Journal of Anaesthesia 2016 116, 829-837DOI: (10.1093/bja/aew071) Copyright © 2016 The Author(s) Terms and Conditions

Fig 5 QST results for all participants. All Δ values are post-injection – pre-injection values. WDT, warmth detection threshold; CDT, cool detection threshold; HPT, heat pain threshold; STH, suprathreshold heat pain perception; PPT, pressure pain threshold. For calculation of WDT, CDT, HPT, STH and PPT see Methods. British Journal of Anaesthesia 2016 116, 829-837DOI: (10.1093/bja/aew071) Copyright © 2016 The Author(s) Terms and Conditions