Influx, CSF-ISF exchange and efflux of glymphatic system: The influx flow of CSF into brain through the para-arterial pathways and then exchange with ISF.

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Presentation transcript:

Influx, CSF-ISF exchange and efflux of glymphatic system: The influx flow of CSF into brain through the para-arterial pathways and then exchange with ISF. The mixed CSF and ISF with interstitial metabolic waste are flowed towards paravenous pathways, and then go to lymphatic system. Influx, CSF-ISF exchange and efflux of glymphatic system: The influx flow of CSF into brain through the para-arterial pathways and then exchange with ISF. The mixed CSF and ISF with interstitial metabolic waste are flowed towards paravenous pathways, and then go to lymphatic system. AQP4 water channels in both arteries and veins play important role in reducing the resistance to CSF movement between paravascular spaces and the interstitium. Reproduced with permission from25. AQP4, astrocytic aquaporin-4; CSF, cerebrospinal fluid; ISF, interstitial fluid. Quan Jiang Stroke Vasc Neurol 2019;svn-2018-000197 © Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.