Does the timing of inhaled dornase alfa matter?

Slides:

Advertisements

Similar presentations

Long-term non-invasive ventilation in cystic fibrosis — Experience over two decades William G. Flight, Jonathan Shaw, Susan Johnson, A. Kevin Webb, Andrew.

Advertisements

Use of the insulin pump in treat cystic fibrosis related diabetes Dana S. Hardin, Julie Rice, Mark Rice, Randall Rosenblatt Journal of Cystic Fibrosis.

Comparing age of cystic fibrosis diagnosis and treatment initiation after newborn screening with two common strategies Don B. Sanders, Huichuan J. Lai,

Effect of dornase alfa on inflammation and lung function: Potential role in the early treatment of cystic fibrosis Michael W. Konstan, Felix Ratjen

Ian D. Molyneux, Tanya Moon, A. Kevin Webb, Alyn H. Morice

Treatment compliance in children and adults with Cystic Fibrosis

Critiquing Cryos by Morie Gertz Blood Volume 111(11):

Peritoneal dialysis American Journal of Kidney Diseases

P. Whitaker, N. Shaw, J. Gooi, C. Etherington, S. Conway, D. Peckham

Towards an individualized protocol for workload increments in cardiopulmonary exercise testing in children and adolescents with cystic fibrosis H.J.

How does heart rate recovery after sub-maximal exercise correlate with maximal exercise testing in children with CF? Sarah P. Cohen, David M. Orenstein

Avani C. Modi, Crystal S. Lim, Nami Yu, David Geller, Mary H

How to Keep the Treatment of Esophageal Disease in the Surgeon’s Hands

Megan R. Nelson, Craig R. Adamski, Audrey Tluczek

A review of renal disease in cystic fibrosis

Urinary incontinence in 9��16��year olds with cystic fibrosis compared to other respiratory conditions and a normal group W.J. Browne, C.J. Wood, M.

Measures of body habitus are associated with lung function in adults with cystic fibrosis: A population-based study Doug L. Forrester, Alan J. Knox,

Laura Viviani, Baroukh M. Assael, Eitan Kerem

Cirrhosis and other liver disease in cystic fibrosis

The ease of breathing test tracks clinical changes in cystic fibrosis

Timing of dornase alpha inhalation does not affect the efficacy of an airway clearance regimen in adults with cystic fibrosis: a randomised crossover.

Adherence to nebulised therapies in adolescents with cystic fibrosis is best on week- days during school term-time Rosemary Ball, Kevin W. Southern, Pamela.

Anju Anand, Elizabeth Tullis, Anne Stephenson, Preyanka Abhyankar

D. Stevens, P.J. Oades, N. Armstrong, C.A. Williams

Claire J. Tipping, Rebecca L. Scholes, Narelle S. Cox

Cystic fibrosis mortality trend in Italy from 1970 to 2011

Influence of digital clubbing on oxygen saturation measurements by pulse-oximetry in cystic fibrosis patients Filip Van Ginderdeuren, Karlien Van Cauwelaert,

The predictive potential of the sweat chloride test in cystic fibrosis patients with the G551D mutation Verena I. Seliger, David Rodman, Fredrick Van.

The end-to-end anastomosis of John B. Murphy

Hypertonic saline and recombinant human DNase: a randomised cross-over pilot study in patients with cystic fibrosis Manfred Ballmann, Horst von der Hardt

A.H. Gifford Journal of Cystic Fibrosis

Treatment of resistant distal intestinal obstruction syndrome with a modified antegrade continence enema procedure I.J. Clifton, A.M. Morton, N.S. Ambrose,

Economic effects of an eradication protocol for first appearance of Pseudomonas aeruginosa in cystic fibrosis patients: 1995 vs. 2009 Yolanda P. Lillquist,

Effectiveness of inhaled tobramycin in eradicating Pseudomonas aeruginosa in children with cystic fibrosis Sanja Stanojevic, Valerie Waters, Joseph L.

Peter König, MD, PhD Journal of Allergy and Clinical Immunology

Inhalation solutions — Which ones may be mixed

Physiologic endpoints for clinical studies for cystic fibrosis

Sophia L. Markantonis, Anna Katelari, Eleni Pappa, Stavros Doudounakis

Colon Cancer in Cystic Fibrosis patients: Is this a growing problem?

Narelle S. Cox, Jennifer Follett, Karen O. McKay

Minutes of the Board of Directors Meeting

Gender differences in treatment adherence among youth with cystic fibrosis: Development of a new questionnaire Joän M. Patterson, Melanie Wall, Jerica.

Disease disclosure in individuals with cystic fibrosis: Association with psychosocial and health outcomes Adrienne P. Borschuk, Robin S. Everhart, Michelle.

Trends in pathogens colonising the respiratory tract of adult patients with cystic fibrosis, 1985–2005 F.A. Millar, N.J. Simmonds, M.E. Hodson Journal.

Volume 69, Issue 12, Pages (June 2006)

C. Van de Kerkhove, P. C. Goeminne, M. Kicinski, T. S. Nawrot, N

Successful treatment of cepacia syndrome with a combination of intravenous cyclosporin, antibiotics and oral corticosteroids Francis J. Gilchrist, A.

V. Thompson, N. Mayer-Hamblett, M. Kloster, D. Bilton, P.A. Flume

Society for Investigative Dermatology 2010 Meeting Minutes

Comparing age of cystic fibrosis diagnosis and treatment initiation after newborn screening with two common strategies Don B. Sanders, Huichuan J. Lai,

Newsome S.J. , Daniel R.M. , Carr S.B. , Bilton D. , Keogh R.H.

J.E. Spahr, R.B. Love, M. Francois, K. Radford, K.C. Meyer

James H. Hull, Rachel Garrod, Timothy B. Ho, Ronald K. Knight, John R

Research Snippets Journal of Investigative Dermatology

Risk factors for Mycobacterium abscessus infection in cystic fibrosis patients; a case– control study Maarten Verregghen, Harry G. Heijerman, Monique.

How Does a Gastroenterologist Demonstrate Value?

Randomized trial of efficacy and safety of dornase alfa delivered by eRapid nebulizer in cystic fibrosis patients Gregory S. Sawicki, Will Chou, Karina.

D.F. Waterhouse, A.M. McLaughlin, C.G. Gallagher

Journal of Investigative Dermatology

The role of respiratory viruses in adult patients with cystic fibrosis receiving intravenous antibiotics for a pulmonary exacerbation C. Etherington,

Volume 55, Pages S3-S16 (June 1999)

CFTR modulators and pregnancy: Our work has only just begun

‘Peeling paint’ dermatitis as a presenting sign of cystic fibrosis

Lutz Goldbeck, Sven Zerrer, Tim G. Schmitz Journal of Cystic Fibrosis

Khin M. Gyi, Margaret E. Hodson, Magdi Y. Yacoub

David Adeboyeku, Sandra Scott, Margaret E. Hodson

Journal of Investigative Dermatology

Elisabeth P. Dellon, Margaret W. Leigh, James R. Yankaskas, Terry L

Volume 55, Pages S41-S46 (June 1999)

Inhaled amiloride and tobramycin solutions fail to eradicate Burkholderia dolosa in patients with cystic fibrosis Ahmet Z. Uluer, David A. Waltz, Leslie.

Presentation transcript:

Does the timing of inhaled dornase alfa matter? Lianne van der Giessen Journal of Cystic Fibrosis Volume 8, Pages S6-S9 (June 2009) DOI: 10.1016/S1569-1993(09)60004-7 Copyright © 2009 European Cystic Fibrosis Society Terms and Conditions

Fig. 1 FEF75% predicted when dornase alfa was inhaled 30 minutes after versus immediately before ACT: results after 3 weeks' treatment. Lines connect individual data points. Bars represent mean values [8]. Reprinted with permission of John Wiley & Sons, Inc. Journal of Cystic Fibrosis 2009 8, S6-S9DOI: (10.1016/S1569-1993(09)60004-7) Copyright © 2009 European Cystic Fibrosis Society Terms and Conditions