Takamatsu I. , Ozaki M. , Kazama T. British Journal of Anaesthesia

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Presentation transcript:

Entropy indices vs the bispectral index™ for estimating nociception during sevoflurane anaesthesia Takamatsu I. , Ozaki M. , Kazama T. British Journal of Anaesthesia Volume 96, Issue 5, Pages 620-626 (May 2006) DOI: 10.1093/bja/ael050 Copyright © 2006 British Journal of Anaesthesia Terms and Conditions

Fig 1 Individual (a) BIS, (b) response entropy (RE) and (c) state entropy (SE) values with increases in end-tidal sevoflurane concentration (ETsev). * and ** indicate significant differences (P<0.05 and 0.01, respectively). British Journal of Anaesthesia 2006 96, 620-626DOI: (10.1093/bja/ael050) Copyright © 2006 British Journal of Anaesthesia Terms and Conditions

Fig 2 Box plots of (a) BIS, (b) response entropy (RE), (c) state entropy (SE) and (d) end-tidal sevoflurane concentration (ETsev) values before skin incision. Box indicates mean and 25% (box top) and 75% (box bottom), whiskers indicate the 5th and 95th percentiles. ‘Movers’ indicates patients who moved after skin incision; ‘nonmovers’ indicates patients who did not. *, **, and *** indicate significant differences (P<0.05, 0.01, and 0.001, respectively). British Journal of Anaesthesia 2006 96, 620-626DOI: (10.1093/bja/ael050) Copyright © 2006 British Journal of Anaesthesia Terms and Conditions

Fig 3 Probability of movement as a function of entropy before skin incision. Solid line is the curve calculated by means of response entropy. Dashed line is the curve calculated by means of state entropy. Probability of 1.0 means all patients move after skin incision, whereas probability of 0 means no patient moves. British Journal of Anaesthesia 2006 96, 620-626DOI: (10.1093/bja/ael050) Copyright © 2006 British Journal of Anaesthesia Terms and Conditions

Fig 4 Difference between response entropy (RE) and state entropy (SE) after electrical stimulation. The differences increased significantly, except with sevoflurane 2.5%. Data are presented as mean (sem). *indicates significant differences (P<0.05) compared with baseline (BL). British Journal of Anaesthesia 2006 96, 620-626DOI: (10.1093/bja/ael050) Copyright © 2006 British Journal of Anaesthesia Terms and Conditions

Fig 5 Relation between response entropy (open circles) or state entropy (closed circles) and BIS. The regression lines are superimposed as a bold (response entropy) or dashed (state entropy) line. British Journal of Anaesthesia 2006 96, 620-626DOI: (10.1093/bja/ael050) Copyright © 2006 British Journal of Anaesthesia Terms and Conditions