From Innovation to Commercialization Access to Data May 9, 2019 Douglas Bell, MD Leader, Informatics Program, Associate Director, UCLA CTSI Professor in Residence, UCLA Department of Medicine www.ctsi.ucla.edu ▪ bringing CTSI innovations to the greatest health needs in Los Angeles 1

How Can I Access EHR Data? Amazing Uses Electronic Health Record Data Contact the CTSI Informatics Program: patientdata@mednet.ucla.edu.

The “Honest Broker” Process for Research Recruitment Outreach Electronic Health Record BedMaster Data Files Contains 74 M Diagnoses 287 M Lab results 82 M Procedures 65 M Medications 57 M Vital Signs …and much more on 2.4 M Patients* MyChart Retrospective Analysis (with Office of Health Informatics & Analytics and CTSI Biostatistics Program) -specific data -specific patients Another 1.8M pts don’t have any structured data Machine Learning (with Office of Health Informatics & Analytics and CTSI Biostatistics Program) REDCap OnCore Gene Chip (2 M SNPs) – IPH Sample

Tools for Self-Service Data Access DDR - Discovery Data Repository Date-shifted version of Epic Caboodle Sites: What You Can Search On: Cedars-Sinai City of Hope UCLA University of Southern California forthcoming: Children’s Hospital Los Angeles Community clinics affiliated with Charles R. Drew University Demographics ICD-9, ICD-10 and CPT Codes Laboratory Tests Medications Visit Details Vital Signs Vital Status Contact the CTSI Informatics Program: patientdata@mednet.ucla.edu.

Tools for Self-Service Data Access Participation by 48 CTSAs Connected to ACT: University of California, San Francisco Boston University Univ of Cincinnati/Cincinnati Children’s Children’s National Univ of Colo/Children’s Hosp. Colorado Columbia University University of Florida Duke University University of Kansas Emory Univ./Morehouse Univ. University of Kentucky Harvard University University of Minnesota Indiana University University of North Carolina at Chapel Hill Johns Hopkins University Mayo Clinic University of Pittsburgh Medical College of Wisconsin University of Southern California Medical University of South Carolina UT Health San Antonio New York University UT Southwestern Northwestern University Vanderbilt University Medical Center Ohio State University Virginia Commonwealth Univ. Oregon Health & Science University Washington University in St. Louis Pennsylvania State University Weill Cornell Medicine Stanford University University of Alabama at Birmingham U. of Arkansas for Medical Sciences University of California, Davis University of California, Irvine University of California, Los Angeles University of California, San Diego Over 440,000 queriable data elements Over 124 million unique patients currently available to query across the network Staging for ACT: University of New Mexico Case Western University University of Rochester Dartmouth College UT Houston Scripps Research / Scripps Health University of Texas Medical Branch Tufts University University at Buffalo University of Utah University of Illinois-Chicago University of Virginia University of Massachusetts University of Washington University of Miami University of Wisconsin-Madison University of Michigan Wake Forest University

Consulting Services See: https://ohia.mednet.ucla.edu See: https://ctsi.ucla.edu Contact the CTSI Informatics Program: patientdata@mednet.ucla.edu.

Programs May 16, 10-11 AM Nearly 300 investigators attended training webinars in 2018 Learn how to: Search 6.5M+ de-identified patient records Expand a study from single to multi-site Obtain patient counts from all institutions w/ one query Inform NIH Inclusion Enrollment Reports w/ patient counts by gender, race and ethnicity Increase cohort identification for rare disease studies Obtain coordinated data provisioning support