SDF-1, adiponectin, and sVCAM levels are higher in Medalists than controls, but SDF-1 does not differ with respect to vascular complications; PAI-1 and IGF-I are lower in Medalists than controls. SDF-1, adiponectin, and sVCAM levels are higher in Medalists than controls, but SDF-1 does not differ with respect to vascular complications; PAI-1 and IGF-I are lower in Medalists than controls. SDF-1 plasma levels in (A) controls and Medalists, (B) Medalists by CVD, and (C) Medalists by PDR. D: IGF-I plasma levels in controls and Medalists. E: Negative correlation between CPCs and IGF-I levels in Medalists. Plasma levels of (F) PAI-1, (G) adiponectin, and (H) sVCAM-1 in controls and Medalists. Graphs show mean, SD. Significance represents Kruskal–Wallis test; P < 0.05. Medalists without CVD, n = 105 of 167; Medalists with CVD, n = 62 of 167; Medalists without PDR, n = 80 of 167; Medalists with PDR, n = 87 of 167; controls, n = 44; Medalists, n = 172. Sonia L. Hernandez et al. Dia Care 2014;37:2193-2201 ©2014 by American Diabetes Association