Follicular thyroid cells of autoimmune thyroiditis may coexpress ICAM-1 (CD54) and its natural ligand LFA-1 (CD11a/CD18) Marcello Bagnasco, MDa, Giampaola.

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Follicular thyroid cells of autoimmune thyroiditis may coexpress ICAM-1 (CD54) and its natural ligand LFA-1 (CD11a/CD18) Marcello Bagnasco, MDa, Giampaola P. Pesce, BSa, Antonio Caretto, MDb, Francesca Paolieri, MDa, Caterina Pronzato, MDa, Barbara Villaggio, BSc, Carla Giordano, MDd, Corrado Betterle, MDb, G.W. Canonica, MDa Journal of Allergy and Clinical Immunology Volume 95, Issue 5, Pages 1036-1043 (May 1995) DOI: 10.1016/S0091-6749(95)70105-2 Copyright © 1995 Mosby, Inc. Terms and Conditions

FIG. 1 Follicular APAAP staining (red) by the CD54 mAb 84H10 in a patient with HT (original magnification, ×500). Journal of Allergy and Clinical Immunology 1995 95, 1036-1043DOI: (10.1016/S0091-6749(95)70105-2) Copyright © 1995 Mosby, Inc. Terms and Conditions

FIG. 2 Follicular APAAP staining by the CD11a mAb 25.3.1 in a Hashimoto's specimen. Identical results were obtained with the other CD11a mAb (8F2.7) (original magnification, ×500). Journal of Allergy and Clinical Immunology 1995 95, 1036-1043DOI: (10.1016/S0091-6749(95)70105-2) Copyright © 1995 Mosby, Inc. Terms and Conditions

FIG. 3 Follicular CD11a (25.3.1) staining in HT (indirect immunofluorescence-phycoerythrin) (original magnification, ×500). Journal of Allergy and Clinical Immunology 1995 95, 1036-1043DOI: (10.1016/S0091-6749(95)70105-2) Copyright © 1995 Mosby, Inc. Terms and Conditions

FIG. 4 Double immunofluorescence with anti-TPO-positive human serum and CD11a (8F2.7) mAb in a section of HT tissue. Diffuse follicular green fluorescence caused by TPO is apparent; some follicular portions are double-stained (orange fluorescence), that is, LFA-1-positive (arrows). Journal of Allergy and Clinical Immunology 1995 95, 1036-1043DOI: (10.1016/S0091-6749(95)70105-2) Copyright © 1995 Mosby, Inc. Terms and Conditions

FIG. 5 Double staining of a follicular portion with CD11a (25.3.1) and CD54 staining (as indicated by amaranth color) in HT (original magnification, ×1000). Journal of Allergy and Clinical Immunology 1995 95, 1036-1043DOI: (10.1016/S0091-6749(95)70105-2) Copyright © 1995 Mosby, Inc. Terms and Conditions