Transvection Goes Live—Visualizing Enhancer-Promoter Communication between Chromosomes Albert Tsai, Robert H. Singer, Justin Crocker Molecular Cell Volume 70, Issue 2, Pages 195-196 (April 2018) DOI: 10.1016/j.molcel.2018.04.004 Copyright © 2018 Elsevier Inc. Terms and Conditions
Figure 1 Models of Transvection The left panel illustrates the classic genetics model of transvection, whereby the enhancer interacts directly with the promoter in trans to drive transcription. The right panel shows transcriptional hubs formed through cooperative interactions between insulators, enhancers, promoters, and transcription factors. Such hubs contain a common pool of transcription factors that can be shared between enhancers and promoters without direct competition. Molecular Cell 2018 70, 195-196DOI: (10.1016/j.molcel.2018.04.004) Copyright © 2018 Elsevier Inc. Terms and Conditions