Albert Tsai, Robert H. Singer, Justin Crocker Molecular Cell

Slides:

Advertisements

Similar presentations

Structure of a Ubiquitin E1-E2 Complex: Insights to E1-E2 Thioester Transfer Shaun K. Olsen, Christopher D. Lima Molecular Cell Volume 49, Issue 5, Pages.

Advertisements

The Genetic Makeup of the Drosophila piRNA Pathway Dominik Handler, Katharina Meixner, Manfred Pizka, Kathrin Lauss, Christopher Schmied, Franz Sebastian.

HnRNP L and HnRNP A1 Induce Extended U1 snRNA Interactions with an Exon to Repress Spliceosome Assembly Ni-Ting Chiou, Ganesh Shankarling, Kristen W. Lynch.

Individualized Medicine from Prewomb to Tomb Eric J. Topol Cell Volume 157, Issue 1, Pages (March 2014) DOI: /j.cell Copyright.

Mechanistic Insight into Site-Restricted Monoubiquitination of FANCD2 by Ube2t, FANCL, and FANCI Arno F. Alpi, Paul E. Pace, M. Madan Babu, Ketan J. Patel.

What We Talk About When We Talk About Fat Evan D. Rosen, Bruce M. Spiegelman Cell Volume 156, Issue 1, Pages (January 2014) DOI: /j.cell

Molecular and Genetic Properties of Tumors Associated with Local Immune Cytolytic Activity Michael S. Rooney, Sachet A. Shukla, Catherine J. Wu, Gad Getz,

An Ancient Mechanism for Splicing Control: U11 snRNP as an Activator of Alternative Splicing Jens Verbeeren, Elina H. Niemelä, Janne J. Turunen, Cindy.

Maintaining Cell Identity through Global Control of Genomic Organization Gioacchino Natoli Immunity Volume 33, Issue 1, Pages (July 2010) DOI: /j.immuni

Cost of Unneeded Proteins in E. coli Is Reduced after Several Generations in Exponential Growth Irit Shachrai, Alon Zaslaver, Uri Alon, Erez Dekel Molecular.

Nucleation and Transport Organize Microtubules in Metaphase Spindles Jan Brugués, Valeria Nuzzo, Eric Mazur, Daniel J. Needleman Cell Volume 149, Issue.

Eph-Ephrin Bidirectional Signaling in Physiology and Disease Elena B. Pasquale Cell Volume 133, Issue 1, Pages (April 2008) DOI: /j.cell

Distinct Properties of Cell-Type-Specific and Shared Transcription Factor Binding Sites Jason Gertz, Daniel Savic, Katherine E. Varley, E. Christopher.

Telomeric Noncoding RNA TERRA Is Induced by Telomere Shortening to Nucleate Telomerase Molecules at Short Telomeres Emilio Cusanelli, Carmina Angelica.

Evolution of the Cancer Stem Cell Model Antonija Kreso, John E. Dick Cell Stem Cell Volume 14, Issue 3, Pages (March 2014) DOI: /j.stem

IPSC Crowdsourcing: A Model for Obtaining Large Panels of Stem Cell Lines for Screening Mahendra Rao Cell Stem Cell Volume 13, Issue 4, Pages (October.

Human Brown Adipose Tissue Sven Enerbäck Cell Metabolism Volume 11, Issue 4, Pages (April 2010) DOI: /j.cmet Copyright © 2010.

Interplay between HDAC3 and WDR5 Is Essential for Hypoxia-Induced Epithelial- Mesenchymal Transition Min-Zu Wu, Ya-Ping Tsai, Muh-Hwa Yang, Chi-Hung Huang,

The Metabolic Basis of Pulmonary Arterial Hypertension Gopinath Sutendra, Evangelos D. Michelakis Cell Metabolism Volume 19, Issue 4, Pages (April.

The BCL-2 Family Reunion Jerry E. Chipuk, Tudor Moldoveanu, Fabien Llambi, Melissa J. Parsons, Douglas R. Green Molecular Cell Volume 37, Issue 3, Pages.

CDK Inhibitors: Cell Cycle Regulators and Beyond Arnaud Besson, Steven F. Dowdy, James M. Roberts Developmental Cell Volume 14, Issue 2, Pages

The Mitochondrial Basis of Aging Nuo Sun, Richard J. Youle, Toren Finkel Molecular Cell Volume 61, Issue 5, Pages (March 2016) DOI: /j.molcel

Shaping Genetic Alterations in Human Cancer: The p53 Mutation Paradigm Thierry Soussi, Klas G. Wiman Cancer Cell Volume 12, Issue 4, Pages (October.

Kinase-Independent Function of Cyclin E Yan Geng, Young-Mi Lee, Markus Welcker, Jherek Swanger, Agnieszka Zagozdzon, Joel D. Winer, James M. Roberts, Philipp.

The Nucleoplasmin Homolog NLP Mediates Centromere Clustering and Anchoring to the Nucleolus Jan Padeken, María José Mendiburo, Sarantis Chlamydas, Hans-Jürgen.

Gastrulation Movements: the Logic and the Nuts and Bolts Maria Leptin Developmental Cell Volume 8, Issue 3, Pages (March 2005) DOI: /j.devcel

Inter-chromosomal Contact Properties in Live-Cell Imaging and in Hi-C

Volume 49, Issue 1, Pages 3-5 (January 2013)

Volume 13, Issue 1, Pages 5-6 (January 2011)

HuD Stimulates Translation via eIF4A

Structural Insights into Riboswitch Control of the Biosynthesis of Queuosine, a Modified Nucleotide Found in the Anticodon of tRNA Mijeong Kang, Robert.

Engineering the End: DNA Processing at Human Telomeres

Skill Development in Graduate Education

The Case of the Disappearing Drug Target

How To Choose a Good Scientific Problem

Natalya A. Ortolano, Vivian Gama Molecular Cell

A New Link in the Chain from Amino Acids to mTORC1 Activation

A Metabolic (Re-)Balancing Act

Volume 13, Issue 1, Pages 5-6 (January 2011)

P Bodies and the Control of mRNA Translation and Degradation

Transvection Current Biology

Karin Johanna Ferrari, Elisa Lavarone, Diego Pasini Molecular Cell

Life after MOMP Molecular Cell

lncRNA Structure: Message to the Heart

William G. Kaelin, Peter J. Ratcliffe Molecular Cell

Eukaryotic Transcription Activation: Right on Target

MicroRNAs and Viral Infection

Volume 49, Issue 2, Pages (January 2013)

A Method that Will Captivate U

Gene Regulation: Hacking the Network on a Sugar High

New Insights into Genome Structure: Genes of a Feather Stick Together

Structural Insights into Riboswitch Control of the Biosynthesis of Queuosine, a Modified Nucleotide Found in the Anticodon of tRNA Mijeong Kang, Robert.

Competition by the Masses

Volume 60, Issue 3, Pages (November 2015)

Volume 36, Issue 2, Pages (October 2009)

In This Issue Molecular Therapy Volume 16, Issue 4, (April 2008)

Regulated Formation of lncRNA-DNA Hybrids Enables Faster Transcriptional Induction and Environmental Adaptation Sara C. Cloutier, Siwen Wang, Wai Kit.

Learning from the Uncontrollable

Volume 22, Issue 4, Pages (April 2018)

How To Choose a Good Scientific Problem

Volume 61, Issue 2, Pages (January 2016)

Chaos Controlled: Discovery of a Powerful Amyloid Inhibitor

Volume 25, Issue 2, Pages (January 2007)

TFII-IΔ and TFII-Iβ: Unequal Brothers Fostering Cellular Proliferation

A Host MicroRNA Brokers Truce with HSV-1

David Hubel and Torsten Wiesel

Volume 63, Issue 6, Pages (September 2016)

Volume 74, Issue 2, Pages (April 2019)

In This Issue Cell Volume 145, Issue 3, (April 2011)

53BP1 Goes Back to Its p53 Roots

Presentation transcript:

Transvection Goes Live—Visualizing Enhancer-Promoter Communication between Chromosomes Albert Tsai, Robert H. Singer, Justin Crocker Molecular Cell Volume 70, Issue 2, Pages 195-196 (April 2018) DOI: 10.1016/j.molcel.2018.04.004 Copyright © 2018 Elsevier Inc. Terms and Conditions

Figure 1 Models of Transvection The left panel illustrates the classic genetics model of transvection, whereby the enhancer interacts directly with the promoter in trans to drive transcription. The right panel shows transcriptional hubs formed through cooperative interactions between insulators, enhancers, promoters, and transcription factors. Such hubs contain a common pool of transcription factors that can be shared between enhancers and promoters without direct competition. Molecular Cell 2018 70, 195-196DOI: (10.1016/j.molcel.2018.04.004) Copyright © 2018 Elsevier Inc. Terms and Conditions