Comparison of Clinical and Neurophysiologic Responses to Intrathecal Baclofen Bolus Administration in Moderate-to-Severe Spasticity After Acquired Brain.

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Comparison of Clinical and Neurophysiologic Responses to Intrathecal Baclofen Bolus Administration in Moderate-to-Severe Spasticity After Acquired Brain Injury  Dobrivoje S. Stokic, MD, Stuart A. Yablon, MD, Antonio Hayes, R.EDT/EPT  Archives of Physical Medicine and Rehabilitation  Volume 86, Issue 9, Pages 1801-1806 (September 2005) DOI: 10.1016/j.apmr.2005.03.027 Copyright © 2005 American Congress of Rehabilitation Medicine and the American Academy of Physical Medicine and Rehabilitation Terms and Conditions

Fig 1 The ratio between maximum soleus H-reflex and M-wave amplitudes (H/M) before (pre-ITB) and at about 5 hours after ITB bolus injection (post-ITB) for more and less involved sides in 30 subjects with acquired brain injury. Two vertical lines define lower and upper limits of 99% confidence interval for H/M ratio (60%–74%) obtained in 30 young healthy subjects. Note that in the majority of subjects the H/M ratio substantially decreased after the injection. Archives of Physical Medicine and Rehabilitation 2005 86, 1801-1806DOI: (10.1016/j.apmr.2005.03.027) Copyright © 2005 American Congress of Rehabilitation Medicine and the American Academy of Physical Medicine and Rehabilitation Terms and Conditions

Fig 2 The number of F waves recorded from 48 trials (F-wave persistence) in abductor hallucis muscle on the more involved side before (pre-ITB) and about 5 hours after ITB bolus injection (post-ITB). Note that F-wave persistence decreased in most subjects, but in 6 it clearly increased (broken line). Archives of Physical Medicine and Rehabilitation 2005 86, 1801-1806DOI: (10.1016/j.apmr.2005.03.027) Copyright © 2005 American Congress of Rehabilitation Medicine and the American Academy of Physical Medicine and Rehabilitation Terms and Conditions