Supplementary Fig. S1. A summary of the suggested mechanism underlying asthma. PAR2, activated by a protease-containing allergen, induces the generation.

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Supplementary Fig. S1. A summary of the suggested mechanism underlying asthma. PAR2, activated by a protease-containing allergen, induces the generation of ROS, which then degrades tight junction proteins and facilitates TSLP-Th2 inflammation via DC modulation in bronchial epithelial cells. PAR2, protease-activated receptor 2; ROS, reactive oxygen species; TSLP, thymic stromal lymphopoietin; DC, dendritic cell; Th2, T helper 2. Supplementary Fig. S1. A summary of the suggested mechanism underlying asthma. PAR2, activated by a protease-containing allergen, induces the generation of ROS, which then degrades tight junction proteins and facilitates TSLP-Th2 inflammation via DC modulation in bronchial epithelial cells… Allergy Asthma Immunol Res. 2019 Jul;11(4):560-571. https://doi.org/10.4168/aair.2019.11.4.560