Cure of HIV infection: Is the long wait over?

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Presentation transcript:

Cure of HIV infection: Is the long wait over? William T. Shearer, MD, PhD Journal of Allergy and Clinical Immunology Volume 134, Issue 1, Pages 20-22 (July 2014) DOI: 10.1016/j.jaci.2014.04.013 Copyright © 2014 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 1 Computer-generated image of HIVgp120 trimer spike (outlined in black lines) projecting from the surface of CD4+ T cell (shown partially at bottom in grey) bound by (coded, eg, PG9, CH01) recombinant broad neutralizing antibodies for specific targets (starting at top and proceeding clockwise): 1) v1v2-glycan (yellow), 2) gp41 (pink), 3) gp41 (orange), 4) CD4 binding site (green), and 5) v3-glycan (gold). Blue colored objects represent the glycan shield. Used with permission from Haynes et al.4 Journal of Allergy and Clinical Immunology 2014 134, 20-22DOI: (10.1016/j.jaci.2014.04.013) Copyright © 2014 American Academy of Allergy, Asthma & Immunology Terms and Conditions