a b Calcium signal (F/F0) Calcium signal (F/F0) Supplementary Figure 1

Slides:

Advertisements

Similar presentations

Signal Transduction. Figure 15-3 Figure 15-4 Table 15-1a.

Advertisements

Effects of NGF. Developmental processes during which apoptosis can occur.

Phase Difference = Phase Difference = 0.05.

P247. Figure 9-1 p248 Figure 9-2 p251 p251 Figure 9-3 p253.

Anti-Apoptotic Effects of Caspase Inhibitors on Rat Intervertebral Disc Cells by Jong-Beom Park, In-Chul Park, Sung-Jin Park, Hyeon-Ok Jin, Jin-Kyung Lee,

Programmed cell Death سخنران : آقای محسن نجاری کارشناس ارشدآزمایشگاه انگل شناسی بیمارستان قائم ( عج )

Ion specific effects in bundling and depolymerization of taxol-stabilized microtubules (MTs) Cyrus R. Safinya, University of California-Santa, DMR

Robbins’ Basic Pathology th Ed. Histology of Chronic Inflammation.

Supplementary Figure 1. Suzuki et al. DAPI/BrdU BrdU 24 hrs 48 hrs 72 hrs.

Tao Lin and Jasneet Kaur Lab Advisor: Dr. Edward Bonder Teaching Assistant: Susan Seipel.

Shimura Supplemental Figure 1

Supplementary figure 5.

Supplementary Figure S1, Lecoeur et al.

Date of download: 10/13/2017 Copyright © ASME. All rights reserved.

From: Activation of the Rho/Rho Kinase Signaling Pathway Is Involved in Cell Death of Corneal Endothelium Invest. Ophthalmol. Vis. Sci ;57(15):

Date of download: 10/24/2017 Copyright © ASME. All rights reserved.

Pathogenesis, Diagnosis, and Treatment of Alcoholic Liver Disease

Temporal Gene Expression Profiles after Focal Cerebral Ischemia in Mice Zhang Chengjie 1, 2, 3 ;Zhu Yanbing 2 ;Wang Song 2, 3 ;Zachory Wei Zheng 1, 2,

Date of download: 11/9/2017 Copyright © ASME. All rights reserved.

Supplementary Figure 1 (log fold change relative to untreated control)

A. B. Supplemental Figure S2. A. Cell cycle G1/S Growth Factor Regulation. Publically available data from (20;

. - t !!l t. - 1f1f J - /\/\ - ' I __.

Cell death in cartilage

Control SC236(5mM) SC236(5mM) SC236(25mM) SC236(25mM)

Calcium regulates ERK nuclear association, but not its activation.

Study may improve survival of transplanted livers

Angiogenesis Inhibitors

Surviving the Cytochrome Seas

A B Supplementary Figure 3

TNF enhances dose‐dependent cell death following doxorubicin‐induced DNA damage with minimal affect on dose‐dependent cell‐cycle arrest. TNF enhances dose‐dependent.

.. '.. ' 'i.., \. J'.....,....., ,., ,,.. '"'". ' · · f.. -··-·· '.,.. \...,., '.··.. ! f.f.

Microtubule Flux: What Is It Good for?

Volume 141, Issue 6, Pages (December 2011)

β-CTT promotes microtubule dynamics.

Supplementary Figure S2

Inhibition of Aurora B Kinase Blocks Chromosome Segregation, Overrides the Spindle Checkpoint, and Perturbs Microtubule Dynamics in Mitosis Marko J.

Death Becomes Us: Apoptosis and Carcinogenesis

Life after MOMP Molecular Cell

B A D C * * E F Panc-1 cells Figure S1 DNA ladder h

Sophie Dumont, Timothy J. Mitchison Current Biology

New Probes for Microtubule Dynamics

Microtubule Assembly and Disassembly

George T. Kannarkat, Dean J. Tuma, Pamela L. Tuma

A20 inhibits caspase-8 cleavage and TRAIL-induced apoptosis.

Edwina S. Baskin–Bey, Gregory J. Gores Gastroenterology

Richard G. Carroll, Seamus J. Martin Cancer Cell

Hip1 and Hippi Participate in a Novel Cell Death-Signaling Pathway

(apoptotic + necrotic)

Supplementary Figures

Pathogenesis, Diagnosis, and Treatment of Alcoholic Liver Disease

TOR signaling regulates microtubule structure and function

RIP3 Finds Partners in Crime

PARP-1, a determinant of cell survival in response to DNA damage

Kin I Kinesins Are Microtubule-Destabilizing Enzymes

A B Supplementary Figure S1 PC3 cells Vehicle 3β-Adiol

Apoptosis Cell Volume 108, Issue 2, Pages (January 2002)

UA62784 Is a Cytotoxic Inhibitor of Microtubules, not CENP-E

Fig. 1 LB100 and LB102 specifically inhibit PP2A phosphatase activity and the growth of BCR-ABL+ cells. LB100 and LB102 specifically inhibit PP2A phosphatase.

Figure 1 Extrinsic and intrinsic pathways of apoptosis

Nitric oxide and apoptosis in mesangial cells

LGN Blocks the Ability of NuMA to Bind and Stabilize Microtubules

A possible mechanism of renal cell death after ischemia/reperfusion

Supplementary Figure S1

Function of the mitotic Ran GPS in spindle assembly.

Volume 11, Issue 19, Pages (October 2001)

Study may improve survival of transplanted livers

Inhibition of polymerization Enhancement of polymerization

Mitotic catastrophe symptoms caused by curcumin are followed by apoptosis. Mitotic catastrophe symptoms caused by curcumin are followed by apoptosis. A.

MicroTUB(B3)ules and Brain Development

Antagonizing XIAP-mediated caspase-3 inhibition

Presentation transcript:

a b Calcium signal (F/F0) Calcium signal (F/F0) Supplementary Figure 1 EXECUTION PHASE SECONDARY NECROSIS 2.2 2.2 2.0 AMN depolymerization 2.0 AMN polymerization 1.8 1.8 1.4 TMRM (F/F0) Calcium signal (F/F0) 1.4 1.2 1.2 1.0 1.0 0.8 0.8 0.6 0.6 -60 -50 -40 -30 -20 -10 10 20 b Time (min) EXECUTION PHASE 1 hour ZOMBIE CELL hours/days 2.2 2.2 2.0 2.0 D 1.8 AMN polymerization 1.8 1.4 TMRM (F/F0) 1.4 Calcium signal (F/F0) 1.2 1.2 1.0 1.0 0.8 0.8 0.6 0.6 -60 -50 -40 -30 -20 -10 10 20 Time (min) Microtubule stabilization: Taxol Caspase inhibition: Zn2+ Antioxidant: Coenzyme Q Apoptotic stabilizer (zombie cocktail) 10 Supplementary Figure 1