The biocompatibility of neutral pH, low-GDP peritoneal dialysis solutions: benefit at bench, bedside, or both?  Jeffrey Perl, Sharon J. Nessim, Joanne.

Slides:



Advertisements
Similar presentations
Urea and nitrogen excretion in pediatric peritoneal dialysis patients
Advertisements

Benefits of switching from a conventional to a low-GDP bicarbonate/lactate-buffered dialysis solution in a rat model  Siska Mortier, Dirk Faict, Norbert.
Improved patient/technique survival and peritonitis rates in patients treated with automated peritoneal dialysis when compared to continuous ambulatory.
Buffer transport in peritoneal dialysis
Use of hemodialysis and hemoperfusion in poisoned patients
Volume 84, Issue 5, Pages (November 2013)
End-stage renal disease in developing countries
Long-term follow-up of patients randomized to biocompatible or conventional peritoneal dialysis solutions show no difference in peritonitis or technique.
Impact of new dialysis solutions on peritonitis rates
The risk of hospitalization and modality failure with home dialysis
Fibrin plug Kidney International Volume 78, Issue 9, (November 2010)
C-reactive protein and dialysis access
Volume 75, Issue 11, Pages (June 2009)
3,4-di-deoxyglucosone-3-ene promotes leukocyte apoptosis
Ho-Han Wu, Szu-Yuan Li, Wu-Chang Yang  Kidney International 
Fluid overload and residual renal function in peritoneal dialysis: the proof of the pudding is in the eating  Wim Van Biesen, Achim Jörres  Kidney International 
Jeffrey C. Fink, Glenn M. Chertow  Kidney International 
Volume 83, Issue 5, Pages (May 2013)
Volume 77, Issue 1, Pages 5-6 (January 2010)
Volume 64, Issue 5, Pages (November 2003)
Methotrexate in the urine
S.G. John, N.M. Selby, C.W. McIntyre  Kidney International 
Comorbidity and confounding in end-stage renal disease
Early mortality in dialysis and adequacy of predialysis renal care: the picture is more complex than we thought  Nicolas Rognant, Maurice Laville  Kidney.
The importance of increased dialysis and anemia management for infant survival in pregnant women on hemodialysis  Sai Subhodhini Reddy, Jean L. Holley 
Volume 74, Issue 3, Pages (August 2008)
Volume 70, Issue 11, Pages (December 2006)
Volume 77, Issue 2, Pages (January 2010)
Nephrology Crosswords: Hemodialysis
The epidemiology of chronic kidney disease
Benefits of preserving residual renal function in peritoneal dialysis
The renin–angiotensin–aldosterone system in peritoneal dialysis: is what is good for the kidney also good for the peritoneum?  Sharon J. Nessim, Jeffrey.
Volume 73, Pages S5-S17 (April 2008)
Improved patient/technique survival and peritonitis rates in patients treated with automated peritoneal dialysis when compared to continuous ambulatory.
Nephrology Crossword: History of nephrology
Volume 70, Issue 7, Pages (October 2006)
Disaster nephrology: crush injury and beyond
A physician's perseverance uncovers problems in a key nephrology study
Clifford J. Holmes, Dirk Faict  Kidney International 
Volume 69, Issue 12, Pages (June 2006)
Volume 69, Issue 3, Pages (February 2006)
Tilman B. Drüeke, Ziad A. Massy  Kidney International 
Microbiology and outcomes of peritonitis in North America
Alternate-day dialysis may be needed for hemodialysis patients
Nephrology Crossword: Peritoneal Dialysis
Benefits of switching from a conventional to a low-GDP bicarbonate/lactate-buffered dialysis solution in a rat model  Siska Mortier, Dirk Faict, Norbert.
Calcium sensing in podocytes
Volume 62, Issue 2, Pages (August 2002)
Nephrology Crossword: Glomerulonephritis
Volume 73, Pages S72-S75 (April 2008)
A man with a hole in his penis
Volume 73, Issue 9, Pages (May 2008)
Volume 82, Issue 9, Pages (November 2012)
Urea and nitrogen excretion in pediatric peritoneal dialysis patients
Peter G. Blake, Arsh K. Jain, Sechelle Yohanna  Kidney International 
Volume 70, Pages S84-S90 (November 2006)
Does equal care give equal outcomes?
Volume 55, Pages S3-S16 (June 1999)
Volume 83, Issue 4, Pages (April 2013)
Volume 80, Issue 10, Pages (November 2011)
Victoria R. Briggs, Badri M. Shrestha, Martin E. Wilkie 
Innovative teaching tools in nephrology
Volume 81, Issue 8, Pages (April 2012)
Dana V. Rizk, David G. Warnock  Kidney International 
The international realities of live donor kidney transplantation
Volume 70, Issue 10, Pages (November 2006)
The International Pediatric Peritonitis Registry: Starting to walk
Where vaptans do and do not fit in the treatment of hyponatremia
Volume 75, Issue 8, Pages (April 2009)
Survival of propensity matched incident peritoneal and hemodialysis patients in a United States health care system  Victoria A. Kumar, Margo A. Sidell,
Presentation transcript:

The biocompatibility of neutral pH, low-GDP peritoneal dialysis solutions: benefit at bench, bedside, or both?  Jeffrey Perl, Sharon J. Nessim, Joanne M. Bargman  Kidney International  Volume 79, Issue 8, Pages 814-824 (April 2011) DOI: 10.1038/ki.2010.515 Copyright © 2011 International Society of Nephrology Terms and Conditions

Figure 1 The GDP content among commercially available neutral pH, low-GDP peritoneal dialysis solutions (solutions 1–4) compared with the GDP content of conventional peritoneal dialysis solutions (solution 5). 3-DG, 3-deoxyglucosone; 3,4-DGE, 3,4-dideoxyglucosone-3-ene; 5-HMF, 5-hydroxymethyl furaldehyde; AcA, acetaldehyde; FoA, formaldehyde; GDP, glucose degradation product. *GDP concentrations for conventional peritoneal dialysis solutions (solution 5) were taken as an average from published values for Gambrosol, StaySafe, and Dianeal. All solutions are prepared using a commercially available 2.5% glucose concentration peritoneal dialysis solution. Total GDP content as measured by the summation of the individual glucose degradation products measured. Adapted from Erixon M. et al.10 Kidney International 2011 79, 814-824DOI: (10.1038/ki.2010.515) Copyright © 2011 International Society of Nephrology Terms and Conditions