Overview of autoimmunity

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Presentation transcript:

Overview of autoimmunity Overview of autoimmunity An autoimmune episode starts (A) with the initiation or reactivation of an immune attack directed against self. The T-cells expand and traffic (B) to the site where the antigen is found, are activated and damage the tissue (C). With time, the response is regulated and subsides, although the immune memory remains (D). Future infection may then trigger a relapse of the remission (E). Lindsay B. Nicholson Essays Biochem. 2016;60:275-301 ©2016 by Portland Press Ltd