Fulminant Hepatic Failure Secondary to Erlotinib

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Presentation transcript:

Fulminant Hepatic Failure Secondary to Erlotinib Weitian Liu, Frederick L. Makrauer, Amir A. Qamar, Pasi A. Jänne, Robert D. Odze Clinical Gastroenterology and Hepatology Volume 5, Issue 8, Pages 917-920 (August 2007) DOI: 10.1016/j.cgh.2007.04.014 Copyright © 2007 AGA Institute Terms and Conditions

Figure 1 Medium-power photograph of the liver showing severe active hepatitis with marked portal inflammation, consisting of lymphocytes, plasma cells, and neutrophils. The portal tracts also show bile ductular proliferation, piecemeal necrosis, and hepatocyte loss in the periportal and lobular region. In other areas, there was severe bridging necrosis. These findings are most consistent with drug toxicity. Clinical Gastroenterology and Hepatology 2007 5, 917-920DOI: (10.1016/j.cgh.2007.04.014) Copyright © 2007 AGA Institute Terms and Conditions