Fig. 6 Wound closure rate, as characterized by the time for 50% wound closure (t1/2) with various reported wound dressings. Wound closure rate, as characterized.

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Fig. 6 Wound closure rate, as characterized by the time for 50% wound closure (t1/2) with various reported wound dressings. Wound closure rate, as characterized by the time for 50% wound closure (t1/2) with various reported wound dressings. Comparisons include AAD (data reported in Fig. 4), microgels (25), chitosan (35), dopamine-modified polyacrylamide (PAAm-Dopa) (50), gelatin (51), alginate-gelatin hydrogels (52), carbon nanotube–laden chitosan hydrogels (chitosan-CNT) (53), polycaprolactone nanofibrous matrix (PCL) (54), hyaluronan (HA), and chondroitin sulfate (CS) hydrogels (55). The half-life time (t1/2) resulting from chondroitin sulfate hydrogels was beyond 20 days. While AAD and microgels were tested in a rodent wound model with splints, most previous reports did not use splinting. S. O. Blacklow et al. Sci Adv 2019;5:eaaw3963 Copyright © 2019 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution License 4.0 (CC BY).