Intensified ovarian stimulation in a GnRH antagonist protocol with agonist triggering: a prospective, clinical feasibility study  Georg Griesinger, Henriette.

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Presentation transcript:

Intensified ovarian stimulation in a GnRH antagonist protocol with agonist triggering: a prospective, clinical feasibility study  Georg Griesinger, Henriette Berndt, Laura Schultz, Askan Schultze-Mosgau, Klaus Diedrich, Sören von Otte  Reproductive BioMedicine Online  Volume 22, Issue 2, Pages 133-139 (February 2011) DOI: 10.1016/j.rbmo.2010.10.017 Copyright © 2010 Reproductive Healthcare Ltd. Terms and Conditions

Figure 1 Schematic representation of the study protocol. ET=embryo transfer; GnRH=gonadotrophin-releasing hormone; HCG=human chorionic gonadotrophin; MPA=medroxyprogesterone acetate; OHSS=ovarian hyperstimulation syndrome; 2PN=2 pronuclear. Reproductive BioMedicine Online 2011 22, 133-139DOI: (10.1016/j.rbmo.2010.10.017) Copyright © 2010 Reproductive Healthcare Ltd. Terms and Conditions

Figure 2 Regression analysis of the relationship between the number of oocytes retrieved and number of fertilized oocytes available for cryopreservation. Line represents quadratic model of the regression equation. Reproductive BioMedicine Online 2011 22, 133-139DOI: (10.1016/j.rbmo.2010.10.017) Copyright © 2010 Reproductive Healthcare Ltd. Terms and Conditions

Figure 3 Box plots of the assessment of physical wellbeing on day 3 or 4 after oocyte retrieval by a visual analogue scale. Assessment based on 26 returned questionnaires. Reproductive BioMedicine Online 2011 22, 133-139DOI: (10.1016/j.rbmo.2010.10.017) Copyright © 2010 Reproductive Healthcare Ltd. Terms and Conditions

Figure 4 (A) Cumulative incidence of a positive human chorionic gonadotrophin test resulting in a live-born baby. (B) Cumulative incidence of live birth according to vitrified–warmed embryo transfer cycle rank. Dashed lines=intention-to-treat excluding spontaneous pregnancies (n=30); solid lines=patients undergoing at least one vitrified–warmed embryo transfer cycle (n=26). Reproductive BioMedicine Online 2011 22, 133-139DOI: (10.1016/j.rbmo.2010.10.017) Copyright © 2010 Reproductive Healthcare Ltd. Terms and Conditions

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