False-positive skin prick test responses to commercially available dog dander extracts caused by contamination with house dust mite (Dermatophagoides.

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Presentation transcript:

False-positive skin prick test responses to commercially available dog dander extracts caused by contamination with house dust mite (Dermatophagoides pteronyssinus) allergens  Maurits J. van der Veen, MDa,b, Marcel Mulderb, Agnes M. Witteman, MD, PhDa, Ronald van Ree, PhDb, Rob C. Aalberse, PhDb, Henk M. Jansen, MD, PhDa, Jaring S. van der Zee, MD, PhDa  Journal of Allergy and Clinical Immunology  Volume 98, Issue 6, Pages 1028-1034 (December 1996) DOI: 10.1016/S0091-6749(96)80187-4 Copyright © 1996 Mosby, Inc. Terms and Conditions

FIG. 1 RAST and RAST inhibition with concentrated dog dander solid phase. A, Inhibition of concentrated dog dander RAST with HDM extract. I to X, Sera of patients I to X with false-positive dog dander SPT responses. B, Inhibition of concentrated dog dander RAST with a dog dander extract. I to IV, Sera of patients I to IV with false-positive dog dander SPT responses. 0-a and 0-b, Serum of a control patient allergic to dogs, which was diluted to a concentration with binding similar to uninhibited RAST of patient I and patients II to IV, respectively. Journal of Allergy and Clinical Immunology 1996 98, 1028-1034DOI: (10.1016/S0091-6749(96)80187-4) Copyright © 1996 Mosby, Inc. Terms and Conditions

FIG. 1 RAST and RAST inhibition with concentrated dog dander solid phase. A, Inhibition of concentrated dog dander RAST with HDM extract. I to X, Sera of patients I to X with false-positive dog dander SPT responses. B, Inhibition of concentrated dog dander RAST with a dog dander extract. I to IV, Sera of patients I to IV with false-positive dog dander SPT responses. 0-a and 0-b, Serum of a control patient allergic to dogs, which was diluted to a concentration with binding similar to uninhibited RAST of patient I and patients II to IV, respectively. Journal of Allergy and Clinical Immunology 1996 98, 1028-1034DOI: (10.1016/S0091-6749(96)80187-4) Copyright © 1996 Mosby, Inc. Terms and Conditions