Fig. 1. Detection of circulating tumor DNA in CRPC patients.

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Fig. 1. Detection of circulating tumor DNA in CRPC patients. Detection of circulating tumor DNA in CRPC patients. (A) Study profile showing the number of patients and samples with next-generation sequencing data and with a circulating tumor DNA fraction ≥0.075. Twenty-six patients (*) and one patient (†) had pre-abiraterone samples only. (B) Correlation of circulating tumor DNA fraction with serum LDH, serum ALP, and AR copy number. Alessandro Romanel et al., Sci Transl Med 2015;7:312re10 Copyright © 2015, American Association for the Advancement of Science