Fig. 6 SNP rs is a functional SNP in 22Rv1 cells.

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Fig. 6 SNP rs55958994 is a functional SNP in 22Rv1 cells. SNP rs55958994 is a functional SNP in 22Rv1 cells. (A) Soft agar colony formation assays comparing WT 22Rv1 cells with (C) allele of rs55958994 and 22Rv1 cells with (T) allele of rs55958994. Quantification is at right. Data represent means ± SEM of three independent experiments. *P < 0.05. (B) Transwell assays in WT 22Rv1 cells with (C) allele of rs55958994 and 22Rv1 cells with (T) allele of rs55958994. Cells that had migrated to lower chambers were stained with 0.1% crystal violet. Quantification is at right. Data represent means ± SEM of three independent experiments. *P < 0.05. (C) FACS analysis of the cell surface markers CD44 and CD24 in WT 22Rv1 cells with (C) allele of rs55958994 and in 22Rv1 cells with (T) allele of rs55958994. Yuyang Qian et al. Sci Adv 2019;5:eaaw6710 Copyright © 2019 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution License 4.0 (CC BY).