Six-year monitoring of the donor-specific immune response to cryopreserved aortic allograft valves: Implications with valve dysfunction Giulio Pompilio,

Slides:

Advertisements

Similar presentations

Aortic Valve Replacement With Patch Enlargement of the Aortic Annulus

Advertisements

Ten-year trends in heart valve replacement operations

Wenrui Ma, MD, Wei Zhang, MD, Wei Shi, MD, Ye Kong, MD, Xinyu Ma, MS

Reply The Annals of Thoracic Surgery

Unusual Gastrointestinal Bleeding After Sutureless Aortic Valve Replacement: A Word of Caution Jules Iquille, MD, Joseph Nader, MD, Eric Colpart, MD,

Outcomes of Reintervention on the Autograft After Ross Procedure

Sreekumar Subramanian, MD, Sergey Leontyev, MD, Michael A

Robert L. Smith, MD, Morley A. Herbert, PhD, Todd M

Immunology and failure of valved allografts in children

Hancock II Bioprosthesis for Aortic Valve Replacement: The Gold Standard of Bioprosthetic Valves Durability? Tirone E. David, MD, Susan Armstrong, MS,

Is a bicuspid aortic valve a risk factor for adverse outcome after an autograft procedure? Ad J.J.C Bogers, MD, PhD, Arie-Pieter Kappetein, MD, PhD,

Effectiveness of Hyperbaric Oxygen Therapy for Hearing Loss After Cardiac Surgery Giuseppe Bruschi, MD, Giuseppe Tarelli, MD, Paola Colombo, MD, PhD,

CTSNet: a unique educational vehicle

Factors Influencing HLA Sensitization in Implantable LVAD Recipients

Aortic valve replacement with the biocor PSB stentless xenograft

Ten-year trends in heart valve replacement operations

Roh Yanagida, MD, PhD, Lawrence S. C. Czer, MD, Nancy L

Long-Term Outcomes of the Mosaic Bioprosthesis

Aortic Valve Replacement With 17-mm St

Which Patients Benefit From Stentless Aortic Valve Replacement?

The “Double-Valve” Sign in Acute Type A Aortic Dissection

Andreas Zierer, MD, Rochus K. Voeller, MD, Karen E

Outcomes of Mechanical Valves in the Pulmonic Position in Patients With Congenital Heart Disease Over a 20-Year Period Hong Ju Shin, MD, Young-Hwue Kim,

Redundant Anterior Aortic Valve

Use of Amiodarone After Major Lung Resection

Are older patients with mechanical heart valves at increased risk?

Zain Khalpey, MD, PhD, Wernard Borstlap, Patrick O. Myers, MD, Jan D

Extracardiac myxoma: An unusual right ventricular epicardial location

Low-Dose Prophylactic Intravenous Immunoglobulin Does Not Prevent HLA Sensitization in Left Ventricular Assist Device Recipients Stavros G. Drakos, MD,

Determinants of Left Ventricular Dysfunction After Repair of Chronic Asymptomatic Mitral Regurgitation Vincent Chan, MD, MPH, Marc Ruel, MD, MPH, Elsayed.

Long-Term Outcomes of Open Arch Repair After a Prior Aortic Operation: Our Experience in 154 Patients Roberto Di Bartolomeo, MD, Paolo Berretta, MD,

Transcatheter Aortic Valve Replacement: How I Teach It

Percutaneous Transcatheter Closure of the Aortic Valve

Redo Aortic Valve Replacement in Children

Robert W. Emery, MD, Christopher C. Krogh, Kit V. Arom, MD, PhD, Ann M

Editorial Board, January 2010

Long-Term Survival and Freedom From Reoperation After Placement of a Pulmonary Xenograft Valved Conduit George M. Alfieris, MD, Michael F. Swartz, PhD,

Aortic Root Replacement for Children With Loeys-Dietz Syndrome

Midterm Outcome of Valve-Sparing Aortic Root Replacement in Inherited Connective Tissue Disorders Hiroshi Tanaka, MD, PhD, Hitoshi Ogino, MD, PhD, Hitoshi.

Bhawna Gupta, PhD, Ali Dodge-Khatami, MD, PhD, Charles D

Surgical Treatment of Aortic Prosthetic Valve Endocarditis: A 20-Year Single-Center Experience Sossio Perrotta, MD, Anders Jeppsson, MD, PhD, Victoria.

Pretransplant Panel Reactive Antibodies in Human Lung Transplantation: An Analysis of Over 10,000 Patients Ashish S. Shah, MD, Lois Nwakanma, MD, Christopher.

Deterioration of a Tricuspid Bioprosthesis Due to Adhesion of the Native Valve Herbert Gutermann, MD, Willem Flameng, MD, PhD, Paul Herijgers, MD, PhD

Hans-Joachim Schäfers, MD, PhD, Diana Aicher, MD, Frank Langer, MD

Transapical Aortic Valve Implantation in High-Risk Patients With Severe Aortic Valve Stenosis Augusto D'Onofrio, MD, Melissa Fusari, MD, Nicola Abbiate,

Surgical Treatment of Aortic Valve Regurgitation Secondary to Ascending Aorta Aneurysm: Is Adjunctive Subcommissural Annuloplasty Necessary? Charles.

The Annals of Thoracic Surgery

Paul Urbanski, MD, PhD The Annals of Thoracic Surgery

David P. Mason, MD, Chase R. Brown, BS, Sudish C

Arnt E Fiane, MD, Odd R Geiran, MD, PhD, Jan L Svennevig, MD, PhD

Twenty-Five Year Outcomes of Tricuspid Valve Replacement Comparing Mechanical and Biologic Prostheses Andrea Garatti, MD, Giovanni Nano, MD, Giuseppe.

Scott B. Johnson, MD, Anna M. Allred, BS, Adam M. Cline, MD, Luis F

Sharven Taghavi, MD, MPH, Senthil N

Total Arterial Off-Pump Coronary Surgery: Time to Change Our Habits?

Postoperative Coronary Artery Spasm Complicating Aortic Valve Replacement: Implications for Identification and Treatment Claudio Pragliola, MD, Luca.

Antibodies to Self-Antigens Predispose to Primary Lung Allograft Dysfunction and Chronic Rejection Ankit Bharat, MD, Deepti Saini, PhD, Nancy Steward,

Steve K. Singh, MD, Gilbert H. L. Tang, MD, Manjula D

Postoperative Cognitive Dysfunction and Aortic Atheroma

Experience With Bovine Pericardium for the Reconstruction of the Aortic Arch in Patients Undergoing a Norwood Procedure Victor O. Morell, MD, Peter A.

Dumbor L. Ngaage, MD, FRCS (C-Th), Michael E. Cowen, FRCS

Cavernous Hemangioma of the Posterior Mediastinum

Aortic Valve Replacement Surgery: Comparison of Outcomes in Matched Sternotomy and PORT ACCESS Groups William T. Brinkman, MD, William Hoffman, MD, Todd.

Small “Functional” Size after Mechanical Aortic Valve Replacement: No Risk in Young to Middle-Age Patients Alfonso Penta de Peppo, MD, Jacob Zeitani,

Is Surgery Always Mandatory for Type A Aortic Dissection?

Aortic root replacement versus aortic valve replacement: a case-match study Paul P Urbanski, MD, Matthias Wagner, MD, Michael Zacher, MD, Robert W Hacker,

Selecting patients with mitral regurgitation and left ventricular dysfunction for isolated mitral valve surgery Constance K. Haan, MD, Cristina I. Cabral,

Risk of Valve-Related Events After Aortic Valve Repair

Heart Transplant Program Volume Is Not a Measure of Quality

Aortic Valve Function After Bicuspidization of the Unicuspid Aortic Valve Diana Aicher, MD, Moritz Bewarder, Michael Kindermann, MD, Hashim Abdul-Khalique,

Michael O. Kayatta, MD, Bradley G

Presentation transcript:

Six-year monitoring of the donor-specific immune response to cryopreserved aortic allograft valves: Implications with valve dysfunction Giulio Pompilio, MD, PhD, GianLuca Polvani, MD, Giuseppe Piccolo, MD, Anna Guarino, BS, Angela Nocco, BS, Annalisa Innocente, Massimo Porqueddu, MD, PhD, Luca Dainese, MD, Fabrizio Veglia, PhD, Andrea Sala, MD, Paolo Biglioli, MD The Annals of Thoracic Surgery Volume 78, Issue 2, Pages 557-563 (August 2004) DOI: 10.1016/j.athoracsur.2004.02.037

Fig 1 Percent of recipients with a positive panel-reactive antibody (PRA) during the follow-up period. (Pts = patients.) The Annals of Thoracic Surgery 2004 78, 557-563DOI: (10.1016/j.athoracsur.2004.02.037)

Fig 2 Kinetics of HLA antibody production, measured as panel-reactive antibody (PRA) activity, after cryopreserved allograft valve replacement. (HLA = human leukocyte antigen; Pts = patients.) The Annals of Thoracic Surgery 2004 78, 557-563DOI: (10.1016/j.athoracsur.2004.02.037)

Fig 3 Freedom from structural deterioration (%) for patients with and without a peak panel-reactive antibody (PRA) more than 80%. PeakPRA > 80% (squares); peakPRA < 80% (triangles). (Pts = patients.) The Annals of Thoracic Surgery 2004 78, 557-563DOI: (10.1016/j.athoracsur.2004.02.037)

Fig 4 Freedom from structural deterioration (%) for patients with and without a 6-year permanent panel-reactive antibody (PRA) more than 70%. PermanentPRA < 70% (triangles); permanentPRA > 70% (squares). (Pts = patients.) The Annals of Thoracic Surgery 2004 78, 557-563DOI: (10.1016/j.athoracsur.2004.02.037)