Tissue distribution of MMP-9 and MMP-2 in adult rat brain.

Slides:



Advertisements
Similar presentations
Date of download: 7/8/2016 Copyright © ASME. All rights reserved. From: Voxelized Model of Brain Infusion That Accounts for Small Feature Fissures: Comparison.
Advertisements

FMRP suppresses dendritic Arc protein levels.
Fig. 3. (A–L) Descriptive representation of Timm staining in the caudal part of dorsal hippocampus and rostral pole of dorsal CA3 subfields. (A–F) Dentate.
Volume 115, Pages (September 2015)
Experimental Neonatal Status Epilepticus and the Development of Temporal Lobe Epilepsy with Unilateral Hippocampal Sclerosis  Mark Dunleavy, Sachiko Shinoda,
Date of download: 10/24/2017 Copyright © ASME. All rights reserved.
Fig. 1. In situ hybridization analysis for detecting endogenous mBest1 transcript in whole-brain region. In situ hybridization results from coronal (top.
Brain Trauma Induces Massive Hippocampal Neuron Death Linked to a Surge in β- Amyloid Levels in Mice Overexpressing Mutant Amyloid Precursor Protein  Douglas.
Desmoplakin is a direct transcriptional target of Bcl11b.
Light micrograph of adult rat brain DAB immunostained for Reelin (blue) and counterstained with neutral red for cells (red). Light micrograph of adult.
FigS3 IHC analysis of Drosha and DGCR8 protein distribution in the hippocampus, frontal cortex and cerebellum of control cases. In the hippocampus both.
Volume 17, Issue 6, Pages (June 2010)
Confocal microscope images of Reelin mRNA detected by in situ hybridization using a biotinylated oligoprobe (base pairs 1264–1311) visualized with fluorescein.
Malat1 is a neuron‐enriched nuclear‐retained ncRNA that is localized to nuclear speckles. Malat1 is a neuron‐enriched nuclear‐retained ncRNA that is localized.
Figure 3 LGI1 and Caspr2 immunohistochemistry on rat brain
Volume 28, Issue 3, Pages (December 2000)
App‐CTFs accumulate in the neurites and synaptic compartments in Aph1abc cKO Cre+ brains App‐CTFs accumulate in the neurites and synaptic compartments.
Figure 1 Reactivity of the patients' antibodies with rat brain and HEK cell-based assays Rat hippocampal dentate gyrus neuropils were stained with patient.
Volume 57, Issue 2, Pages (January 2008)
Seizures in the Developing Brain
Immune Proteins in Brain Development and Synaptic Plasticity
The PPAR-α agonist GW7647 increases the levels of apoA-I in the retina and the fibrous sclera. The PPAR-α agonist GW7647 increases the levels of apoA-I.
Volume 3, Issue 3, Pages (September 2008)
In situ confirmations of Sepw1-enriched genes.
Volume 28, Issue 3, Pages (December 2000)
Subregion- and Cell Type–Restricted Gene Knockout in Mouse Brain
Classification of the 1458 identified proteins into molecular functions. Classification of the 1458 identified proteins into molecular functions. The pie.
Continued. Continued. E, Light microscopic image of the left hippocampus obtained by amygdalohippocampectomy reveals extensive neuronal loss and gliosis.
Morphological studies in the hippocampus of sut mice (A) Low-power images of the hippocampus from WT and sut mice. Morphological studies in the hippocampus.
The effect of ETC duration and temperature on imaging depth.
DFP-induced astrogliosis is reduced by urethane.
Volume 13, Issue 3, Pages (March 2006)
Figure 1 Clinical findings and CNS immunoreactivity of CSF IgA of a patient with limbic encephalitis (A) Cranial MRI of a 69-year-old man with limbic encephalitis.
HDAC4N increases with Braak stage in CA2 hippocampal pyramidal cells.
Volume 57, Issue 2, Pages (January 2008)
Volume 90, Issue 4, Pages (May 2016)
Cross-species comparisons.
SIRT1 is downregulated in human gastric cancer (GC).
Area-specific decrease of KCC2 immunofluorescent staining in slices exposed to the 0-Mg2+ solution. Area-specific decrease of KCC2 immunofluorescent staining.
PTX-induced reporter protein expression in the brain of the IEG reporter line. PTX-induced reporter protein expression in the brain of the IEG reporter.
Fig. 2. Deficiency of neuronal HS leads to reduced neuroinflammation.
Activation of glial cells.
Histology of neurons studied by juxtacellular recordings in CL thalamus. Histology of neurons studied by juxtacellular recordings in CL thalamus. A, B,
OTX2 in RMS and V-SVZ is non-cell-autonomous.
CIE does not alter D2/D4 receptor expression in the mPFC.
Csmd2 mRNA is expressed in the mouse forebrain.
Neuronal and glial expression of Nogo-A and synaptic localization of Nogo-A and NgR 1 in the motor cortex. Neuronal and glial expression of Nogo-A and.
Gene deletion of PGC-1α leads to the loss of dopamine neurons in the SNpc. Gene deletion of PGC-1α leads to the loss of dopamine neurons in the SNpc. A,
miR-9 regulation of Pax6 expression.
PTZ-induced c-Fos and Arc proteins in hippocampal dentate gyrus
Dissection and clearing of brain subregions.
PTZ-induced neuronal activity visualized by IEGs
Spatiotemporal transmission of tau pathology from additional injection site in non-Tg mice. Spatiotemporal transmission of tau pathology from additional.
MFN2 mutants induce abnormal mitochondrial clustering and morphology in cell bodies and proximal axons. MFN2 mutants induce abnormal mitochondrial clustering.
Stress-induced monocyte accumulation in the brain and the neurovascular induction of ICAM-1 were prevented by ADX. Male C57BL/6 mice were subjected to.
Schematic diagram illustrating a theoretical model of amygdala modulation of memory and synaptic plasticity in the hippocampus. Schematic diagram illustrating.
Developmental changes in Scn1a expression and susceptibility to hyperthermia-induced seizures. Developmental changes in Scn1a expression and susceptibility.
ErbB4 expression in PV+ and PV– interneurons and the ErbB4 expression levels in hippocampus of WT and the NRG1tg-type-I mice. ErbB4 expression in PV+ and.
Selective expression of Neurod6 in mDA neurons in the VTA
Smad1 induces target genes in conditioned DRG neurons.
Gene expression changes in the PFC of mice with decreased TrkB expression. Gene expression changes in the PFC of mice with decreased TrkB expression. A-I,
Brain ischemic tolerance model using mouse MCAO
Geographical distribution (A) and historical information (B) for tigers in the Russian Far East that died or were killed due to abnormal neurologic behavior.
Effects of the genotypes of Rapgef2 and Rapgef6 on the apical surface structures. Effects of the genotypes of Rapgef2 and Rapgef6 on the apical surface.
Dendritic morphology of hippocampal CA1 neurons from wild-type and cbdnf ko animals. Dendritic morphology of hippocampal CA1 neurons from wild-type and.
Gdx rats exhibit increased BDNF-ir in the MF pathway.
A, B, 5-HT1A immunoreactivity in hippocampal dendrites (CA3) of saline-treated (A) and fluoxetine-treated (B) rats. A, B, 5-HT1A immunoreactivity in hippocampal.
BDNF protein is expressed in neurons and astrocytes of hippocampus after pilocarpine-induced SE. A, Representative confocal images of hippocampal subfields.
Densin knock-out mice have normal gross neuroanatomy and low body weight. Densin knock-out mice have normal gross neuroanatomy and low body weight. A,
Activation and expression of the transgene.
Presentation transcript:

Tissue distribution of MMP-9 and MMP-2 in adult rat brain. Tissue distribution of MMP-9 and MMP-2 in adult rat brain. Sections of dorsal hippocampus demonstrating the distribution of MMP-9 and MMP-2 mRNA and protein are shown.A, Nissl staining of a hippocampal coronal section.mol. layer, Molecular layer; lacun. mol., lacunosum molecular layer; rad., radiatum layer. Scale bar, 1 mm. B, Tissue distribution of MMP-9 mRNA (in situ hybridization; left image) and protein (immunohistochemistry; right image). MMP-9 mRNA is enriched in neuronal fields of the hippocampus. The right image shows enrichment of MMP-9 protein in neuronal bodies of the dentate gyrus and the CA subfields. Diffuse MMP-9 protein staining, especially in the lacunosum molecular layer, can also be discerned.C, Tissue distribution of MMP-2 mRNA (left image) and protein (right image). In contrast to MMP-9, MMP-2 mRNA and protein are diffusely distributed over the entire hippocampus. Arek Szklarczyk et al. J. Neurosci. 2002;22:920-930 ©2002 by Society for Neuroscience