This Month in Gastroenterology Jan Tack, John M. Carethers  Gastroenterology  Volume 135, Issue 5, Pages 1435-1438 (November 2008) DOI: 10.1053/j.gastro.2008.10.003 Copyright © 2008 AGA Institute Terms and Conditions

Figure 1 Proportions of patients with clinical remission of collagenous colitis at months 2, 4, and 6 of maintenance therapy with oral budesonide 6 mg once daily or placebo. Gastroenterology 2008 135, 1435-1438DOI: (10.1053/j.gastro.2008.10.003) Copyright © 2008 AGA Institute Terms and Conditions

Figure 2 Probability of survival free of liver transplantation in the 3 subgroups of patients while treated with UDCA according to the severity of portal hypertension (PHG <6 [no portal hypertension], 6–12 [moderate portal hypertension], and >12 mmHg [severe portal hypertension]). Gastroenterology 2008 135, 1435-1438DOI: (10.1053/j.gastro.2008.10.003) Copyright © 2008 AGA Institute Terms and Conditions

Figure 3 miR-192 inhibition of macrophage inflammatory peptide-2a (MIP-2a) mRNA and protein expression. TNF-α–induced MIP-2a mRNA expression (A) and protein secretion (B) were significantly reduced in HT29 cells transfected with miR-192 mimic. The control mimic had no effect (*P < .005; **P < .001). Gastroenterology 2008 135, 1435-1438DOI: (10.1053/j.gastro.2008.10.003) Copyright © 2008 AGA Institute Terms and Conditions

Figure 4 Functional activities of apical membrane Na+/H+ and Cl−/HCO3− in intact villous epithelium. (A) Na+/H+ exchange (Nhe) activity in wild type (WT), down-regulated in adenoma (Dra) knockout (KO), and Nhe3 KO jejunum as measured by removal and replacement of luminal Na+ (representative of 3 mice). (B) Cl−/HCO3− exchange activity in WT, Nhe3 KO, and Dra KO measured by removal and replacement of luminal Cl− (representative of 3 mice). Gastroenterology 2008 135, 1435-1438DOI: (10.1053/j.gastro.2008.10.003) Copyright © 2008 AGA Institute Terms and Conditions