Vasomotor symptoms in infertile premenopausal women: a hitherto unappreciated risk for low bone mineral density Lubna Pal, M.B., B.S., John Norian, M.D.,

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Vasomotor symptoms in infertile premenopausal women: a hitherto unappreciated risk for low bone mineral density Lubna Pal, M.B., B.S., John Norian, M.D., Gohar Zeitlian, M.D., Kris Bevilacqua, Ph.D., Ruth Freeman, M.D., Nanette Santoro, M.D. Fertility and Sterility Volume 90, Issue 5, Pages 1626-1634 (November 2008) DOI: 10.1016/j.fertnstert.2007.08.020 Copyright © 2008 American Society for Reproductive Medicine Terms and Conditions

Figure 1 Higher prevalence of low BMD in premenopausal women experiencing vasomotor symptoms. Fertility and Sterility 2008 90, 1626-1634DOI: (10.1016/j.fertnstert.2007.08.020) Copyright © 2008 American Society for Reproductive Medicine Terms and Conditions

Figure 2 Relationship between worsening ovarian reserve (i.e., higher FSH levels) and bone metabolism: Fertility and Sterility 2008 90, 1626-1634DOI: (10.1016/j.fertnstert.2007.08.020) Copyright © 2008 American Society for Reproductive Medicine Terms and Conditions

Figure 3 An up-regulation of bone turnover, as reflected by serum levels of N-telopeptide (a) and the composite bone turnover score (b), is noted in premenopausal infertile women experiencing night sweats. BCE = bone collagen equivalents. Fertility and Sterility 2008 90, 1626-1634DOI: (10.1016/j.fertnstert.2007.08.020) Copyright © 2008 American Society for Reproductive Medicine Terms and Conditions