F. Jauréguy, E. Carbonnelle, S. Bonacorsi, C. Clec'h, P. Casassus, E

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Host and bacterial determinants of initial severity and outcome of Escherichia coli sepsis  F. Jauréguy, E. Carbonnelle, S. Bonacorsi, C. Clec'h, P. Casassus, E. Bingen, B. Picard, X. Nassif, O. Lortholary  Clinical Microbiology and Infection  Volume 13, Issue 9, Pages 854-862 (September 2007) DOI: 10.1111/j.1469-0691.2007.01775.x Copyright © 2007 European Society of Clinical Infectious Diseases Terms and Conditions

Fig. 1 Projections of 34 bacterial variables (▴), including the virulence factors (Δ) and the clinical variables (▪), characterised in the 161 Escherichia coli isolates, on the plane F1/F2 computed from the factorial analysis of correspondence. The virulence factors are: papC, P fimbriae; papGII, PapG class II adhesin; papGIII, PapG class III adhesin; sfa/foc, S fimbriae; hlyC, haemolysin; cnf1, cytotoxic necrotising factor; iucC, iron uptake system (IUS) aerobactin; fyuA, IUS yersiniabactin; and iroN, IUS salmochelin. The clinical variables are labelled as follows: fema, female; male, male; <65, age <65 years; >65, age >65 years; UTO, urinary tract origin; DTO, digestive tract origin; OTO, other tract origin; UNO, unknown origin; sepsis, severe sepsis, septic shock; DEA, death; DAS, death attributed to sepsis; HM, haematological malignancy; DIA, diabetes; NEO, neoplasia; RFA, renal failure; ICO, immunocompetent host; ICH, immunocompromised host; noso, nosocomial infection; com, community-acquired infection; SXT, trimethoprim-sulphamethoxazole; AMX, amoxycillin; OFX, ofloxacin. Clinical Microbiology and Infection 2007 13, 854-862DOI: (10.1111/j.1469-0691.2007.01775.x) Copyright © 2007 European Society of Clinical Infectious Diseases Terms and Conditions