Effect of pre-exposure to sevoflurane on the bispectral index in women undergoing Caesarean delivery under general anaesthesia W.J. Choi, S.H. Kim, W.U.

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Effect of pre-exposure to sevoflurane on the bispectral index in women undergoing Caesarean delivery under general anaesthesia W.J. Choi, S.H. Kim, W.U. Koh, D.I. Hwang, S.K. Cho, P.H. Park, S.M. Han, J.W. Shin British Journal of Anaesthesia Volume 108, Issue 6, Pages 990-997 (June 2012) DOI: 10.1093/bja/aes036 Copyright © 2012 The Author(s) Terms and Conditions

Fig 1 The time line for the study protocol. British Journal of Anaesthesia 2012 108, 990-997DOI: (10.1093/bja/aes036) Copyright © 2012 The Author(s) Terms and Conditions

Fig 2 The end-tidal sevoflurane concentrations at each event. *The target concentration of sevoflurane was attained more rapidly in the preSevo 1 group than in the control 2 group (P=0.003). British Journal of Anaesthesia 2012 108, 990-997DOI: (10.1093/bja/aes036) Copyright © 2012 The Author(s) Terms and Conditions

Fig 3 BIS values in the period before Caesarean delivery. The mean BIS values in the preSevo 1 and 2 groups were maintained below 60 in the period before delivery. BI, before intubation; SI, skin incision; UI, uterine incision. Values are mean (sd). *P<0.05 vs control 1 group. †P<0.05 vs control 2 group. British Journal of Anaesthesia 2012 108, 990-997DOI: (10.1093/bja/aes036) Copyright © 2012 The Author(s) Terms and Conditions

Fig 4 Proportions (success rates) of patients achieving BIS values <60 in the period before Caesarean delivery. Success rates were significantly higher in the preSevo than in the control groups. British Journal of Anaesthesia 2012 108, 990-997DOI: (10.1093/bja/aes036) Copyright © 2012 The Author(s) Terms and Conditions

Fig 5 Haemodynamic parameters in the period before Caesarean delivery. Apart from a change in MAP at the time of skin incision, which was significantly smaller in the preSevo 2 group than in the control 2 group, there was no significant difference in MAP or HR among groups. SI, skin incision; UI, uterine incision. Values are means with sds. *P<0.05 vs control 1 group. †P<0.05 vs control 2 group. British Journal of Anaesthesia 2012 108, 990-997DOI: (10.1093/bja/aes036) Copyright © 2012 The Author(s) Terms and Conditions