Allergic fungal sinusitis: An immunohistologic analysis

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Presentation transcript:

Allergic fungal sinusitis: An immunohistologic analysis David A. Khan, MDa, D.Thane Cody, MDa, Terry J. George, MAc, Gerald J. Gleich, MDb, Kristin M. Leiferman, MDc Journal of Allergy and Clinical Immunology Volume 106, Issue 6, Pages 1096-1101 (December 2000) DOI: 10.1067/mai.2000.110929 Copyright © 2000 Mosby, Inc. Terms and Conditions

Fig. 1 A, H&E staining of allergic fungal sinusitis tissue (patient 3), showing sinus mucosa (upper) and allergic mucin (lower) in an area in which the epithelium is mainly intact (original magnification, 160×). B, GMS staining of allergic fungal sinusitis tissue, showing fungal elements (arrows) within allergic mucin (original magnification, 160×). Sinus culture from surgery grew Alternaria species. C, Eosinophil granule MBP staining (patient 3, serial section of tissue in A ), showing prominent extracellular MBP deposition in allergic mucin (lower) and predominantly cellular staining in sinus mucosa (upper ; original magnification, 160×). D, Neutrophil elastase staining (patient 3, serial section of tissue in C ), showing prominent extracellular deposition in allergic mucin and predominantly cellular staining in sinus mucosa (original magnification, 160×). E, Mast cell tryptase staining (patient 3, se-rial section of tissue in D ), showing several mast cells in sinus mucosa without cellular or extracellular staining in allergic mucin (original magnification, 160×). Journal of Allergy and Clinical Immunology 2000 106, 1096-1101DOI: (10.1067/mai.2000.110929) Copyright © 2000 Mosby, Inc. Terms and Conditions