Sequence comparisons of fungal HOG1 orthologues.

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Sequence comparisons of fungal HOG1 orthologues. Sequence comparisons of fungal HOG1 orthologues. (A) Multiple-sequence alignment of the indicated Hog1 sequences using Clustal Omega and visualized using Jalview. The top graph shows the sequence conservation: columns are highlighted with the same color where there is conservation across the compared sequences. The graph at the bottom tracks the conservation with identical amino acid sequences highlighted in yellow. C. au; C. auris, C. al; C. albicans, C. d; C. dubliniensis; S. p; S. pombe, S. c; S. cerevisiae, C. g; C. glabrata. (B) Sequence alignment of the C-terminal Hog1 sequences from C. auris, S. cerevisiae, and C. glabrata. (C) Hog1 mobility. Western blot depicting the size of Hog1 orthologues from the indicated fungal species. The predicted size of each orthologue is shown (kDa). Alison M. Day et al. mSphere 2018; doi:10.1128/mSphere.00506-18