Fig. 4 Univariate fMRI analysis.

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Fig. 4 Univariate fMRI analysis. Univariate fMRI analysis. Top: Contrast image representing between-group differences (responders > nonresponders) of neural encoding of the weighted RPE (P < 0.05 FWE). Responders exhibit greater activity in the right amygdala (A) and right striatum (B). Coordinates are given in the MNI (Montreal Neurological Institute) space. Bottom: Scatterplots [n = 26 (19 responders and 7 nonresponders)] representing robust linear correlation between posttreatment residualized BDI scores (that is, adjusted for the pretreatment BDI score) and subject-specific average parameter estimates extracted from two clusters pertaining to the right amygdala (C) and right striatum (D). Filippo Queirazza et al. Sci Adv 2019;5:eaav4962 Copyright © 2019 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution License 4.0 (CC BY).