Bio-Rad Overview and Statement of Interests

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Presentation transcript:

Bio-Rad Overview and Statement of Interests

Bio-Rad Overview Leading global provider of sophisticated products for life science research & clinical diagnostics markets Founded in 1952 Develop, manufacture and market products to enable discovery Diversified and complimentary mix of products & technologies Sales exceeded $2 billion in 2015 Nearly 65 years of strong performance Offices and facilities around the world More than 8,000 employees worldwide Listed on the NYSE (BIO)

Business Segments Life Science & Clinical Diagnostics Manufacture and distribute 10,000+ products >80% of sales from products in which Bio-Rad has a leading market position Develop strong, long-lasting relationships with our customers Products help people live longer, healthier lives Cont…

Life Science Group Products used in genomics, proteomics, cell biology, life science education and food safety Separation, purification and analysis of biological materials More than 5,000 products Strong relationships with the research community Natural linkage to clinical diagnostics

Circle of Discovery Genotyping & Gene Expression (PCR & qPCR) Gene Transfer & Modulation Protein Expression (multi-analyte detection) Protein Quantification (western blotting) Food Safety (food pathogen testing) Biological research can be categorized into 3 fundamental areas: Cell Biology, Genomics, Proteomics. While Bio-Rad products are integral to all of these areas of research, we have focused primarily on the study of genes and proteins. There is an increasing interest, on the part of our customers, to study cells and we have now turned some of our attention to the growing area of cell analysis and recently introduced new products in this area. Customers include universities and medical schools, industrial research organizations, government agencies, pharmaceutical manufacturers, biotechnology researchers, food producers and food testing laboratories. Protein Purification (chromatography) Digital Biology (Droplet Digital PCR) Cellular Imaging Cell Sorting & Analysis 9

Revolutionizing Science Bio-Rad is a leader in digital genomics Innovative technologies provide digital answers to complex biological questions 100s of peer-reviewed publications Applications in life science research & diagnostics Our core droplet partitioning technology is enabling breakthroughs in Our Digital Biology Group, with centers is Pleasanton, California and Cambridge, Massachusetts are seeing applications of this technology center around cancer-rare mutation detection-and residual disease monitoring. Sensitivity and precision of ddPCR is proving to be an enabling support technology This new technology continues to grow in popularity as evidenced not only by placements of our QX 200 instrument but also publications about the use of this technology (100s of peer-reviewed publications so far)… Liquid biopsy Cancer genotyping Biomarker detection Environmental monitoring Prenatal testing Pathogen detection Single-cell sequencing 6

Focus Areas – Life Science Research Products and technologies that complement our core leadership in Life Sciences and digital biology Single cell biology (genomics and proteomics) Protein characterization Digital genomics and translational research New generation sequencing technology

Needs – Life Science Research Core benefit: Targeting new technologies / technical approaches that provide complete solutions to our customers in Life Science Research Core value: Product / application should provide well defined benefits for researchers over existing products - with simplified workflows and ease of use Target population: Academic researchers, biotechnology and pharmaceutical researchers, food safety and science educators Target market: Large and growing and falling into a focus area Technical considerations: Instrument target costs Consumable target costs Technology should be scalable for manufacturing Maximal IP protection for the individual technology / application Regulatory requirements should be met globally Safety profile of technology compatible with product use

Clinical Diagnostics Group Products for medical screening and diagnostics More than 3,000 products “Gold Standard” products Leadership positions Quality Control Systems Immunohematology Diabetes Monitoring HIV/Hepatitis Autoimmune Testing Products for laboratory diagnostics to diagnose a variety of human disorders. Bio-Rad is a leading specialty diagnostics company. Products incorporate a broad range of technologies used to detect, identify, and quantify substances in bodily fluids and tissues. Results are used as aids to support medical diagnosis, detection, evaluation and the monitoring and treatment of diseases and other medical conditions.

An Integrated Systems Approach Quality controls Infectious disease AIDS/HIV Blood Virus detection Bacteriology Diabetes monitoring Genetic disease screening Autoimmune testing Blood typing Specialized Testing Instruments Products consist of instruments and reagents typically provided to the customer as integrated package to allow a lab to generate reproducible test results. In the center area are the primary markets we target; we have leading market positions in several areas: Leader in A1C testing (considered the gold standard) Leader in autoimmune testing (the BioPlex 2200 instrument) Leader in quality controls (considered the gold standard) important to the lab, work on all instruments Blood typing – able to serve small and large labs Customers are primarily hospital labs, reference, labs, transfusion labs, and physician office labs worldwide. Diagnostic Tests Quality Controls 7

Focus Areas – Clinical Diagnostics Products and technologies that will have strong growth potential in the future of health care Microbiome Point of care technologies Microbiology, including antibiotic susceptibility New biomarkers Food safety Wearables, mHealth

Needs – Clinical Diagnostics Core benefit: Targeting new diagnostic tests that provide clinicians and health care providers a complete solutions (assay + instrument) Core value: Product / application should provide benefits for clinical labs over existing products - with simplified workflows and ease of use Target population: Commercial diagnostic labs, blood banks, hospitals, and emerging testing labs Target market: Large and growing and falling into a focus area Technical considerations: Instrument and consumable target costs Assay complexity, precision and sensitivity Technology should be scalable for manufacturing Reimbursement plan needs to be defined Maximal IP protection Regulatory requirements should be met globally Safety profile of technology compatible with product use