OMV-enriched proteins show a conserved N-terminal LES motif. OMV-enriched proteins show a conserved N-terminal LES motif. The top 91 OMV-enriched proteins (a) and top 24 OM-enriched proteins (b) were aligned using the lipoprotein attachment cysteine at the +1 position (not shown in the logo), followed by the 9 C-terminal contiguous residues. The lipoprotein export sequence (LES) consensus was generated using WebLogo (https://weblogo.berkeley.edu/logo.cgi) (56). Ezequiel Valguarnera et al. mSphere 2018; doi:10.1128/mSphere.00559-18