Matthew R. Gingo, MD, MS, Sally E

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Presentation transcript:

Asthma diagnosis and airway bronchodilator response in HIV-infected patients  Matthew R. Gingo, MD, MS, Sally E. Wenzel, MD, Chad Steele, PhD, Cathy J. Kessinger, RN, Lorrie Lucht, BS, Tammi Lawther, BS, Michelle Busch, MLT, Maria E. Hillenbrand, MS, Renee Weinman, BS, William A. Slivka, RPFT, Deborah K. McMahon, MD, Yingze Zhang, PhD, Frank C. Sciurba, MD, Alison Morris, MD, MS  Journal of Allergy and Clinical Immunology  Volume 129, Issue 3, Pages 708-714.e8 (March 2012) DOI: 10.1016/j.jaci.2011.11.015 Copyright © 2011 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 1 Prevalence of respiratory symptoms (A) and pulmonary function values (B) in participants given a diagnosis of asthma by their physicians in the past and those without an asthma diagnosis. Values are presented as percent predicted. Journal of Allergy and Clinical Immunology 2012 129, 708-714.e8DOI: (10.1016/j.jaci.2011.11.015) Copyright © 2011 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 2 Prevalence of a high (>2.3%) eosinophil count in induced sputum between participants with or without doctor-diagnosed asthma or positive BDR results. Journal of Allergy and Clinical Immunology 2012 129, 708-714.e8DOI: (10.1016/j.jaci.2011.11.015) Copyright © 2011 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig E1 Prevalence of respiratory symptoms (A) and pulmonary function values (B) in participants with and without BDR. Values are presented as percent predicted. Journal of Allergy and Clinical Immunology 2012 129, 708-714.e8DOI: (10.1016/j.jaci.2011.11.015) Copyright © 2011 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig E2 Associations of chemokines with bronchodilator response and pulmonary function tests. A and B, Probability of BDR with low versus high plasma MIP-1α (Fig E2, A) or sputum MIP-1β (Fig E2, B) levels. C, Change in FEV1 with low versus high plasma MIP-1β levels. Journal of Allergy and Clinical Immunology 2012 129, 708-714.e8DOI: (10.1016/j.jaci.2011.11.015) Copyright © 2011 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig E3 Association between high eosinophil percentages (>2.3%) and high sputum MIP-1β levels. Journal of Allergy and Clinical Immunology 2012 129, 708-714.e8DOI: (10.1016/j.jaci.2011.11.015) Copyright © 2011 American Academy of Allergy, Asthma & Immunology Terms and Conditions