Transcriptional promiscuity in testes

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Presentation transcript:

Transcriptional promiscuity in testes Edward E Schmidt Current Biology Volume 6, Issue 7, Pages 768-769 (July 1996) DOI: 10.1016/S0960-9822(02)00589-4

Figure 1 (a) Three hypothetical promoters with different assemblies of transcription factors. The dissociation constants for the interaction of each promoter with holoenzyme are set at 100, 5 and 0.5 arbitrary units for promoters A, B and C, respectively. The holoenzyme and the promoter complexes are assumed to be stable within the range of conditions modeled. (b) Relative promoter activities at a holoenzyme concentration of 1.0 arbitrary units. (c) Changes in holoenzyme concentration differentially affect the activities of the promoters without changing the affinities of the promoters for holoenzyme. Current Biology 1996 6, 768-769DOI: (10.1016/S0960-9822(02)00589-4)