Fig. 4 Reconstitution of MCs in KitW-sh/W-sh mice increases IL-10+ Breg cells and suppresses the CHS response. Reconstitution of MCs in KitW-sh/W-sh mice.

Slides:

Advertisements

Similar presentations

Fig. 5 Correlation of RNA expression and protein abundance.

Advertisements

Fig. 4 Altitudinal distributions of ice thickness change (m year−1) for the 650 glaciers. Altitudinal distributions of ice thickness change (m year−1)

Fig. 4 The extracellular domain of sortilin is sufficient for BDNF/TrkB signaling. The extracellular domain of sortilin is sufficient for BDNF/TrkB signaling.

Fig. 2 Transport properties of a BP transistor at low temperature.

Fig. 3 Sortilin deletion unmasks NTSR2 signaling.

Fig. 1 KCC2 down-regulation is prevented in sortilin-deficient mice.

Fig. 2 Global production, use, and fate of polymer resins, synthetic fibers, and additives (1950 to 2015; in million metric tons). Global production, use,

Vibrational spectra of medieval human bones (Leopoli-Cencelle, Italy)

Fig. 5 Thermal conductivity of n-type ZrCoBi-based half-Heuslers.

Fig. 1 Map of water stress and shale plays.

Fig. 2 Exercise training potentiates synaptic transmissions via mTOR activation. Exercise training potentiates synaptic transmissions via mTOR activation.

Fig. 1 Examples of experimental stimuli and behavioral performance.

Fig. 4 Resynthesized complex boronic acid derivatives based on different scaffolds on a millimole scale and corresponding yields. Resynthesized complex.

Fig. 6 Comparison of properties of water models.

Fig. 1 Mean and median RCR (Relative Citation Ratio) of Roadmap Epigenomics Program research articles for each year. Mean and median RCR (Relative Citation.

Fig. 2 Reference-fixing experiment, results.

Fig. 3 Scan rate effects on the layer edge current.

Fig. 3 Rotation experiment, setup.

Fig. 1 Product lifetime distributions for the eight industrial use sectors plotted as log-normal probability distribution functions (PDF). Product lifetime.

Fig. 1 Reference-fixing experiment, setup.

Fig. 6 SNP rs is a functional SNP in 22Rv1 cells.

Fig. 1 Parameterization and temporal distribution of carbon isotopic events in the database. Parameterization and temporal distribution of carbon isotopic.

Fig. 1 Distribution of total and fake news shares.

Fig. 6 Maternally derived type 2 CD4+T cells are enriched in NbM dam milk and are required for transfer of protection. Maternally derived type 2 CD4+T.

Fig. 6 Activating IRF8 promotes macrophage migration during the recovery phase after SCI. Activating IRF8 promotes macrophage migration during the recovery.

Fig. 3 Characteristics of UV and temperature sensors.

Fig. 2 2D QWs of different propagation lengths.

Fig. 5 Molecular dynamics simulations of Rac1.

Fig. 6 WPS imaging of different chemical components in living cells.

Fig. 4 Cdc42 enhances the cellular uptake of EVs.

Fig. 4 DFT ωB97x/def2-TZVPP atomic charges on the sulfur atom of substituted thioaldehyde and AIMNet prediction with a different number of iterative passes.

Fig. 5 Simultaneous absence of caspase-3 and -7 is required for significant decrease of caspase-8 and -9 activation in intrinsic apoptosis. Simultaneous.

Fig. 3 ET dynamics on the control and treatment watersheds during the pretreatment and treatment periods. ET dynamics on the control and treatment watersheds.

Fig. 1 Histograms of the number of first messages received by men and women in each of our four cities. Histograms of the number of first messages received.

Fig. 5 Schematic phase diagrams of Ising spin systems and Mott transition systems. Schematic phase diagrams of Ising spin systems and Mott transition systems.

Fig. 4 OER performance of ACoO3 (A = Ca, Sr) in alkaline solutions with different pH. OER performance of ACoO3 (A = Ca, Sr) in alkaline solutions with.

Fig. 1 Average contribution (million metric tons) of seafood-producing sectors, 2009–2014. Average contribution (million metric tons) of seafood-producing.

Fig. 1 Cross-sectional images of He-implanted V/Cu/V samples.

Fig. 3 Production of protein and Fe(II) at the end of growth correlated with increasing concentrations of ferrihydrite in the media that contained 0.2.

Fig. 2 NH3, NOx, SO2, and NMVOC emission changes triggered by the JJJ clean air policy. NH3, NOx, SO2, and NMVOC emission changes triggered by the JJJ.

Fig. 1 Global occurrences of hydraulic fracturing–induced seismicity and potential models. Global occurrences of hydraulic fracturing–induced seismicity.

Fig. 2 Top 10 countries, ecoregions, conservation hotspots, and KBAs with the largest area of restoration hotspots. Top 10 countries, ecoregions, conservation.

Fig. 5 Comparison of the liquid products generated from photocatalytic CO2 reduction reactions (CO2RR) and CO reduction reactions (CORR) on two catalysts.

Schematic of the proposed brain-controlled assistive hearing device

Fig. 1 Location of the Jirzankal Cemetery.

Fig. 4 CO2 emission changes triggered by the JJJ clean air policy.

Fig. 3 Directional rolling of an NP on a dsDNA fragment with flexibility gradient. Directional rolling of an NP on a dsDNA fragment with flexibility gradient.

Fig. 2 Simulations of possible doping positions and band structures.

Fig. 4 Phase diagram showing significant order parameters ∣pk∣ versus T and wc. Phase diagram showing significant order parameters ∣pk∣ versus T and wc.

Multiplexed four- and eight-channel devices for rapid processing

Fig. 2 Mean field results. Mean field results. (A) Solutions P(x) to Eq. 4 for a range of T and wc = (B) Modulus ∣pk∣ of order parameters versus.

Fig. 6 Stabilization of hippocampal signaling over sleep.

Experimenter gender and replicability in science

Fig. 1 Schematic depiction of a paradigm for rapid and guided discovery of materials through iterative combination of ML with HiTp experimentation. Schematic.

Fig. 4 Spatial mapping of the distribution and intensity of industrial fishing catch. Spatial mapping of the distribution and intensity of industrial fishing.

Fig. 4 Single-particle contact angle measurements.

Fig. 5 IL-5–mediated signaling is critical for the development of CD1dintCD5+ Breg precursor cells and IL-10+ Breg cells. IL-5–mediated signaling is critical.

Fig. 2 Supraballs and films from binary SPs.

Fig. 3 Performance of the generative model G, with and without stack-augmented memory. Performance of the generative model G, with and without stack-augmented.

Fig. 4 Behavior of resistance peak near density nm = 5.

Fig. 2 Comparison between the different reflective metasurface proposals when θi = 0° and θr = 70°. Comparison between the different reflective metasurface.

Fig. 4 Light-induced TRPV1 activation promotes in vitro tubulogenesis in ECFC cultures. Light-induced TRPV1 activation promotes in vitro tubulogenesis.

Fig. 4 Systemic AAV9 delivery of gene editing components to ΔEx44 mice rescues dystrophin expression. Systemic AAV9 delivery of gene editing components.

Fig. 5 Phototransduction mechanisms.

Fig. 1 Doping schematics and optical properties.

Fig. 4 Effects of individual picosecond and microsecond pulses.

Fig. 3 Calculated electronic structure of ZrCoBi.

Fig. 1 Attractive interaction between a doublon and a holon due to antiferromagnetic exchange interactions in half-filled 2D Mott insulators. Attractive.

Fig. 5 CD19-tPSMA(N9del) CAR T cell numbers in mouse and human.

Fig. 1 TH17 cell differentiation was severely impaired in Cxxc1-deficient mice. TH17 cell differentiation was severely impaired in Cxxc1-deficient mice.

Presentation transcript:

Fig. 4 Reconstitution of MCs in KitW-sh/W-sh mice increases IL-10+ Breg cells and suppresses the CHS response. Reconstitution of MCs in KitW-sh/W-sh mice increases IL-10+ Breg cells and suppresses the CHS response. (A) The histograms show the frequencies of total CD19+ B cells in peripheral tissues from WT mice or KitW-sh/W-sh mice with or without the adoptive transfer of MCs. (B and C) Representative plot images show IL-10+ CD19+ B cells (B), and histograms show the frequencies of CD5+CD19+ B cells (C) in peripheral tissues from WT mice or KitW-sh/W-sh mice with or without the adoptive transfer of MCs. (D) Ear thickness, (E) the frequency of IL-10+ B cells, and (F) the number of IL-13+ ILC2s are shown during CHS in WT or KitW-sh/W-sh mice with or without the transfer of MCs. Data are expressed as the mean ± SEM (A and C to F) and representative images (B) from two independent experiments (n ≥ 3 per group for each experiment). *P < 0.05; **P < 0.01; n.s., not significant by Student’s t test (D and F) or one-way ANOVA with post hoc Tukey’s test (C and E). BMMC, bone marrow-derived MC; PDMC, PeC-derived MC. Hyuk Soon Kim et al. Sci Adv 2019;5:eaav8152 Copyright © 2019 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution NonCommercial License 4.0 (CC BY-NC).