Intranasal immunization of mice with S

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Shigella-specific serum IgG and IgA endpoint titers in guinea pigs immunized intranasally with S. flexneri 2a InvaplexNAT or InvaplexAR. Shigella-specific.

Long-chain fatty acids are less abundant in the cecal contents of coconut oil-fed mice than in the cecal contents of beef tallow-fed mice. Long-chain fatty.

Anti-CD40 and CpG induce activation of T cells in draining lymph nodes

Volume 5, Issue 1, Pages (January 2009)

Long-chain fatty acids are less abundant in the cecal contents of coconut oil-fed mice than in the cecal contents of beef tallow-fed mice. Long-chain fatty.

C. albicans murine gastrointestinal colonization is lower in mice fed a diet containing coconut oil than in mice fed a diet containing beef tallow or soybean.

TRF2ΔBΔM induces apoptosis and senescence in the mouse liver.

SEC-HPLC of InvaplexNAT and InvaplexAR.

Effects of senescent cells on activity.

Targeted DNA vaccination induced protection against nasal challenge with influenza virus 14 d after DNA vaccination. Targeted DNA vaccination induced protection.

Fatty acid composition of beef tallow, soybean oil, and coconut oil and weight of mice fed diets containing those fats. Fatty acid composition of beef.

(A) Weight loss curves following intranasal infection of different mouse groups with COBRA, seasonal, or pandemic influenza viruses. (A) Weight loss curves.

Long-lasting protection against nasal challenge with influenza virus 252 d after a single DNA vaccination. Long-lasting protection against nasal challenge.

MFS1 expression in parental and progeny strains.

Rom2 protein levels in the ccr4Δ, khd1Δ ccr4Δ, ccr4Δ mpk1Δ, and khd1Δ ccr4Δ mpk1Δ mutant strains. Rom2 protein levels in the ccr4Δ, khd1Δ ccr4Δ, ccr4Δ.

Dibutyryl cAMP does not rescue staurosporine-induced filamentation of a cyr1Δ/cyr1Δ mutant. Dibutyryl cAMP does not rescue staurosporine-induced filamentation.

DNSP16 mutation attenuates the virulence of a mouse-adapted MERS-CoV strain. dNSP16 mutation attenuates the virulence of a mouse-adapted MERS-CoV strain.

Protection from influenza virus challenge.

COX-2–PGE2 signaling is required for MSC-induced increase in ALDHhigh CSC-enriched population and tumor initiation. COX-2–PGE2 signaling is required for.

Virulence determinants in California S. sonnei isolates.

Phylogeny of Shiga toxin-encoding phage from SDi/SJo S. sonnei isolates. Phylogeny of Shiga toxin-encoding phage from SDi/SJo S. sonnei isolates. (A) progressiveMauve.

Expression response of AT-rich genes to lanthanides.

The pho4Δ mutant is less virulent than the WT strain in intranasal (A to C) and intravenous (D to F) models of cryptococcosis. The pho4Δ mutant is less.

Individual genes exhibit distinct stage-specific expression among female gametocytes. Individual genes exhibit distinct stage-specific expression among.

Coexpression of the adjuvant mmCT with chromosomal RΔ-CTB attenuates the immune response to CTB. (A) Genotype of an O139 serotype vaccine strain in which.

Changing to a coconut oil-containing diet reduces preexisting GI colonization by C. albicans. Changing to a coconut oil-containing diet reduces preexisting.

Volume 5, Issue 1, Pages (January 2009)

Transcriptomic analysis of Jamaican fruit bats infected with Tacaribe virus (TCRV). Transcriptomic analysis of Jamaican fruit bats infected with Tacaribe.

Δcarp mutants have a growth phenotype in vitro and in vivo.

Relative ITS2 abundance of Saccharomyces in stool over time as a Saccharomyces cerevisiae-free diet was consumed. Relative ITS2 abundance of Saccharomyces.

Stress-protective roles of C. auris Hog1.

Antibody reactivity against HA1 proteins after vaccination.

(A) Taxonomic identity at the phylum level of raw leachate (RL) and enrichment microcosms (E) as determined via Ion Torrent 16S rRNA gene amplicon sequencing.

BTG2 regulates gluconeogenic gene expression in diabetic mouse models

Growth of Salmonella and E. coli in egg white.

Dynamic light scattering (DLS) analysis of S

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De novo prions are infectious.

OVA-specific and InvaplexNAT-specific serum IgG endpoint titers in mice after intranasal immunization with OVA alone or OVA combined with InvaplexAR, InvaplexNAT,

A: Chemical structure of pterosin A

MRP2 inhibition mitigates pulmonary burden and bacteremia following lung challenge with S. pneumoniae. MRP2 inhibition mitigates pulmonary burden and bacteremia.

Prime and boosts with PBK001 vaccine provided 100% protection with low bacterial burden in organs. Prime and boosts with PBK001 vaccine provided 100% protection.

TbERP silencing has minimal effect on proliferation.

Comparison of the percentages of ducts in the pancreas containing cells showing positive staining for the different markers between control hamster Ig–and.

SAM transport by Gap4 in S. cerevisiae cells.

Therapeutic effect of IL-12/ms treatment on gonococcal infection depends on both IFN-γ and B cells. Therapeutic effect of IL-12/ms treatment on gonococcal.

Increased pancreatic insulin content and islet size and protection against HFD- and palmitate-induced cell death in PKCδKN-overexpressing mice. Increased.

Deficiency of adipocyte IKKβ does not affect diet-induced weigh gain but results in an exaggerated diabetic phenotype when challenged with an HFD. A: IKKβ.

Heterotrophic and autotrophic particle (cell) abundance in water column. Heterotrophic and autotrophic particle (cell) abundance in water column. Small.

Stress resistance comparisons.

CT production profiles of single-SNP strains and double-, triple-, and quadruple-SNP combination strains. CT production profiles of single-SNP strains.

Cross-protection against variants within a subtype after intranasal immunization with vaccine from MDCK cell-adapted Vac-3 P22. Cross-protection against.

Cytokine changes in LPS-induced TNFα and spontaneous IL-6 production in whole-blood cultures. Cytokine changes in LPS-induced TNFα and spontaneous IL-6.

Deletion of VdHapX renders Verticillium dahliae more susceptible to H2O2. Deletion of VdHapX renders Verticillium dahliae more susceptible to H2O2. (A)

Mice immunized twice with RRBC showed superior protection to tumor challenge with αGal-positive MC38 colon carcinoma cells compared with mock-immunized.

A, tumor growth studies in H1975 tumor–bearing mice.

SskA and sakA are essential for adaptation to cell wall, osmotic, and salt stress. sskA and sakA are essential for adaptation to cell wall, osmotic, and.

B. fragilis utilizes TLR2 signaling for its protective role against the development of colitis-associated cancer in mice. B. fragilis utilizes TLR2 signaling.

Dietary coconut oil inhibits GI colonization by C. albicans.

LAIV enhancement of pneumococcal density is time dependent and long lasting. LAIV enhancement of pneumococcal density is time dependent and long lasting.

PHs of olive brines. pHs of olive brines. The average ± standard deviation (SD) of two independent replicates at each time point is shown. Acetic acid.

IL-17A−/− mice are more susceptible to intravaginal HSV-2 challenge following intranasal immunization. IL-17A−/− mice are more susceptible to intravaginal.

Distribution of selected traits across the >4,000 strains in the most recent version of the database, including cell shape (A), spore formation (B), motility.

Volcano plot analysis of fecal metabolites altered in the ciprofloxacin or vancomycin-imipenem groups at the end of treatment (A) or 9 days after cessation.

Effects of ZOL treatment on pulmonary metastases.

Phylogenetic analysis of complete Fusobacterium genomes.

Colonization with B. fragilis protects mice against development of colon cancer. Colonization with B. fragilis protects mice against development of colon.

Effect on the recall response of Nrp1 deletion before infection.

Primary GBM cells are permissive to HCMV in vitro.

Presentation transcript:

Intranasal immunization of mice with S Intranasal immunization of mice with S. sonnei InvaplexAR induces protective immune responses against S. sonnei and S. flexneri 2a. Intranasal immunization of mice with S. sonnei InvaplexAR induces protective immune responses against S. sonnei and S. flexneri 2a. Mice were immunized intranasally on days 0, 14, and 28 with S. sonnei InvaplexAR, S. sonnei InvaplexNAT, or S. flexneri 2a InvaplexNAT and challenged using the pulmonary mouse model on day 49 with either S. flexneri 2a strain 2457T or S. sonnei strain Moseley. Mice were weighed on the day of challenge and each day for 14 days postchallenge. The average weight for each group was calculated, and the difference was expressed as a percentage of the change in weight from the prechallenge values. K. Ross Turbyfill et al. mSphere 2018; doi:10.1128/mSphere.00583-17