Predicted vertical cup-to-disc ratio (VCDR) when each of the explanatory variables, intraocular pressure (IOP), central corneal thickness (CCT), body mass index (BMI) and body fat percentage (BFP), was varied from average to average ±SD, as calculated by linear mixed model by sex. Predicted vertical cup-to-disc ratio (VCDR) when each of the explanatory variables, intraocular pressure (IOP), central corneal thickness (CCT), body mass index (BMI) and body fat percentage (BFP), was varied from average to average ±SD, as calculated by linear mixed model by sex. Hideki Fukuoka et al. BMJ Open Ophth 2017;1:e000012 © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2016. All rights reserved. No commercial use is permitted unless otherwise expressly granted.