Occurrence and developmental consequences of vacuoles throughout preimplantation development Thomas Ebner, Ph.D., Marianne Moser, Ph.D., Michael Sommergruber,

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Occurrence and developmental consequences of vacuoles throughout preimplantation development Thomas Ebner, Ph.D., Marianne Moser, Ph.D., Michael Sommergruber, M.D., Ute Gaiswinkler, M.D., Omar Shebl, M.D., Klaus Jesacher, M.D., Gernot Tews, M.D. Fertility and Sterility Volume 83, Issue 6, Pages 1635-1640 (June 2005) DOI: 10.1016/j.fertnstert.2005.02.009 Copyright © 2005 American Society for Reproductive Medicine Terms and Conditions

FIGURE 1 Vacuolization throughout preimplantation development. (A) Vacuole (17 μm) in MII oocyte. (B) Ten-μm vacuole at zygote stage. (C) Compacting embryo with severe vacuolization (22–35 μm). (D) Vacuole (17 μm) in the inner cell mass of an expanded blastocyst. CS = cytoplasmic string; V = vacuole. Ebner. Vascuolization throughout development. Fertil Steril 2005. Fertility and Sterility 2005 83, 1635-1640DOI: (10.1016/j.fertnstert.2005.02.009) Copyright © 2005 American Society for Reproductive Medicine Terms and Conditions